HTN3

Gene Symbol	HTN3
Entrez Gene	3347
Alt Symbol	HIS2, HTN2, HTN5
Species	Human
Gene Type	protein-coding
Description	histatin 3
Other Description	PB|basic histidine-rich protein|histatin 5|histatin-3|histatin-4|histatin-5|histatin-6|histatin-7|histatin-8|histatin-9|histidine-rich protein 3|hst
Swissprots	Q16243 P15516 Q502Z1
Accessions	AAA02746 AAB32411 EAX05606 P15516 BC009791 AAH09791 BC095438 AAH95438 BP332860 CB957931 DQ892864 ABM83790 DQ896113 ABM87112 M18372 AAA51830 M26665 AAA58646 NM_000200 NP_000191
Function	Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. His3-(20-43)-peptide (histatin-5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9. {ECO:0000269|PubMed:11179305, ECO:0000269|PubMed:8945538}.
Subcellular Location	Secreted {ECO:0000269|PubMed:14966203}. Note=Secreted by serous acinar and demilune cells.
Top Pathways	Salivary secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Histatin-3 full length protein - ab158710 from Abcam Category Protein Source Wheat germ Species Human

Human Histatin-3 full length protein - ab199580 from Abcam Category Protein Source E. coli Species Human

Recombinant Human Histatin 3 Protein - H00003347-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Histatin-5 - SP2194b from Abgent, a WuXi AppTec company Category Peptide Prices $165.00 Sizes 1 mg

Histatin-5 - SP2194a from Abgent, a WuXi AppTec company Category Peptide Prices $125.00 Sizes 500 µg

Histatin-3-H3 - SP2195b from Abgent, a WuXi AppTec company Category Peptide Prices $285.00 Sizes 1 mg

Histatin-3-H3 - SP2195a from Abgent, a WuXi AppTec company Category Peptide Prices $158.00 Sizes 500 µg

Human HTN3 protein - orb180289 from Biorbyt Category Protein Prices $408.00, $595.00, $2,074.00, $2,933.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Histatin 5 peptide - orb71670 from Biorbyt Category Peptide Prices $536.00 Sizes 5 mg

Histatin 5 Peptide - abx064562 from Abbexa Category Peptide

Histatin-3 - H00003347-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

HTN3 fusion protein - ag8902 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

HTN3 fusion protein - Ag9302 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Histatin 3 (H3) - 54677 from NeoScientific Category Peptide Prices $66.00, $198.00, $590.00 Sizes 1 mg, 5 mg, 10 mg

Histatin 5 - 55224 from NeoScientific Category Peptide Prices $99.00, $165.00 Sizes 5 mg, 10 mg

Histatin 5 Peptide - 350222 from ABBIOTEC Category Peptide Prices $212.00 Sizes 1 mg

Histatin 5 - GWB-FE3EF0 from Genway Biotech Category Peptide Prices $177.00 Sizes 500 µg

Recombinant Histatin 3 (HTN3) - RPC535Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Histatin 5 - 000-001-M58 from Rockland Immunochemicals Inc Category Peptide Prices $199.00 Sizes 1 mg

Histatin 5 - 000-001-M59 from Rockland Immunochemicals Inc Category Peptide Prices $199.00 Sizes 1 mg

Histatin 8 - 000-001-M60 from Rockland Immunochemicals Inc Category Peptide Prices $98.00 Sizes 1 mg

Histatin 5 - CCP1263 from Cohesion Biosciences Category Peptide Prices $132.00, $396.00, $660.00 Sizes 1 mg, 5 mg, 10 mg

Recombinant Histatin 3 (HTN3) - RPC535Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Histatin-3(HTN3) - CSB-YP010879HU CSB-EP010879HU CSB-BP010879HU CSB-MP010879HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Histatin 3 (H3) - abx261985 from Abbexa

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