HTN3

Gene Symbol HTN3
Entrez Gene 3347
Alt Symbol HIS2, HTN2, HTN5
Species Human
Gene Type protein-coding
Description histatin 3
Other Description PB|basic histidine-rich protein|histatin 5|histatin-3|histatin-4|histatin-5|histatin-6|histatin-7|histatin-8|histatin-9|histidine-rich protein 3|hst
Swissprots Q16243 P15516 Q502Z1
Accessions AAA02746 AAB32411 EAX05606 P15516 BC009791 AAH09791 BC095438 AAH95438 BP332860 CB957931 DQ892864 ABM83790 DQ896113 ABM87112 M18372 AAA51830 M26665 AAA58646 NM_000200 NP_000191
Function Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. His3-(20-43)-peptide (histatin-5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9. {ECO:0000269|PubMed:11179305, ECO:0000269|PubMed:8945538}.
Subcellular Location Secreted {ECO:0000269|PubMed:14966203}. Note=Secreted by serous acinar and demilune cells.
Top Pathways Salivary secretion

Histatin 3 CRISPR/Cas9 KO Plasmid (h) - sc-410830 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histatin 3 HDR Plasmid (h) - sc-410830-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histatin 3 Double Nickase Plasmid (h) - sc-410830-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histatin 3 Double Nickase Plasmid (h2) - sc-410830-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histatin 3 CRISPR Activation Plasmid (h) - sc-410830-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histatin 3 CRISPR Activation Plasmid (h2) - sc-410830-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histatin 3 Lentiviral Activation Particles (h) - sc-410830-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histatin 3 Lentiviral Activation Particles (h2) - sc-410830-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histatin 3 siRNA (h) - sc-105456 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Histatin 3 shRNA Plasmid (h) - sc-105456-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Histatin 3 shRNA (h) Lentiviral Particles - sc-105456-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU118381 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10390 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10390 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02674 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02674

HTN3 siRNA (Human) - CRH2280 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HTN3 - MBS828260 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HTN3 (NM_000200.2) - SHH315857 from Creative biogene

Category siRNA
Species Reactivities Human

Human HTN3 siRNA - orb262782 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HTN3 shRNA Plasmid (Human) - CHH2280 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HTN3 miRNA 3'UTR clone - MiUTR4H-TG04355 from Creative biogene

Species Reactivities Human
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