MCM7

Gene Symbol	MCM7
Entrez Gene	4176
Alt Symbol	CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146, PPP1R104
Species	Human
Gene Type	protein-coding
Description	minichromosome maintenance complex component 7
Other Description	CDC47 homolog|DNA replication licensing factor MCM7|homolog of S. cerevisiae Cdc47|minichromosome maintenance deficient 7|protein phosphatase 1, regulatory subunit 104
Swissprots	E9PGN9 A4D2A2 A4D2A1 Q15076 P33993 Q96GL1 Q96D34
Accessions	CBX85483 CDH61696 EAL23855 EAL23856 EAW76598 EAW76599 EAW76600 P33993 AF279900 AAK07555 AI083651 AK055379 BAG51508 AK096959 BAG53399 AK226175 AK293172 BAG56716 AK314575 BAG37153 AY007130 AAG01994 BC009398 AAH09398 BC013375 AAH13375 D55716 BAA09534 D86748 BAH84845 DA253520 DA397394 DA538092 DQ895947 ABM86873 EU176445 ABW03896 X74796 CAA52803 XM_005250348 XP_005250405 NM_001278595 NP_001265524 NM_005916 NP_005907 NM_182776 NP_877577
Function	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage. {ECO:0000269|PubMed:15210935, ECO:0000269|PubMed:15538388, ECO:0000269|PubMed:9305914}.
Subcellular Location	Nucleus {ECO:0000250}.
Top Pathways	DNA replication, Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-MCM7-cDNA-Clone - DC03623 from Abgent, a WuXi AppTec company Prices $970.65 Sizes 10 µg Species Human Accession BC013375

MCM7 - MBS1266208 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC009398

MCM7 - MBS1273038 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC013375

Human MCM7 cDNA clone(NM_182776.1) - CDFG012217 from Creative Biomart Species Human Accession NM_182776.1

Human MCM7 cDNA clone(NM_005916.3) - CDFH011211 from Creative Biomart Species Human Accession NM_005916.3

Human MCM7 ORF Clone(NM_005916.3) - CDCR291603 from Creative Biomart Species Human Accession NM_005916.3

Human MCM7 ORF Clone(NM_005916.3) - CDCR291604 from Creative Biomart Species Human Accession NM_005916.3

Human MCM7 ORF Clone(NM_005916.3) - CDCR291605 from Creative Biomart Species Human Accession NM_005916.3

Human MCM7 ORF Clone(NM_182776.1) - CDCR324790 from Creative Biomart Species Human Accession NM_182776.1

Human MCM7 ORF Clone(NM_182776.1) - CDCR324791 from Creative Biomart Species Human Accession NM_182776.1

Human MCM7 ORF Clone(NM_005916.3) - CDCL169787 from Creative Biomart Species Human Accession NM_005916.3

Human MCM7 ORF Clone(NM_005916.3) - CDCL169788 from Creative Biomart Species Human Accession NM_005916.3

Human MCM7 ORF Clone(NM_005916.3) - CDCL169789 from Creative Biomart Species Human Accession NM_005916.3

Human MCM7 Gene ORF cDNA clone in cloning vector - HG16465-G from Sino Biological Species Human

Human MCM7 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG16465-ACG from Sino Biological Species Human

Human MCM7 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG16465-CF from Sino Biological Species Human

Human MCM7 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG16465-NM from Sino Biological Species Human

Human MCM7 Gene ORF cDNA clone expression plasmid, C-HA tag - HG16465-CY from Sino Biological Species Human

Human MCM7 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG16465-CM from Sino Biological Species Human

Human MCM7 Gene ORF cDNA clone expression plasmid, C-His tag - HG16465-CH from Sino Biological Species Human

Human MCM7 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG16465-ANG from Sino Biological Species Human

Human MCM7 Gene ORF cDNA clone expression plasmid, N-HA tag - HG16465-NY from Sino Biological Species Human

Human MCM7 Gene ORF cDNA clone expression plasmid, N-His tag - HG16465-NH from Sino Biological Species Human

Human MCM7 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG16465-ACR from Sino Biological Species Human

Human MCM7 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG16465-ANR from Sino Biological Species Human

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