MCM7

Gene Symbol	MCM7
Entrez Gene	4176
Alt Symbol	CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146, PPP1R104
Species	Human
Gene Type	protein-coding
Description	minichromosome maintenance complex component 7
Other Description	CDC47 homolog|DNA replication licensing factor MCM7|homolog of S. cerevisiae Cdc47|minichromosome maintenance deficient 7|protein phosphatase 1, regulatory subunit 104
Swissprots	E9PGN9 A4D2A2 A4D2A1 Q15076 P33993 Q96GL1 Q96D34
Accessions	CBX85483 CDH61696 EAL23855 EAL23856 EAW76598 EAW76599 EAW76600 P33993 AF279900 AAK07555 AI083651 AK055379 BAG51508 AK096959 BAG53399 AK226175 AK293172 BAG56716 AK314575 BAG37153 AY007130 AAG01994 BC009398 AAH09398 BC013375 AAH13375 D55716 BAA09534 D86748 BAH84845 DA253520 DA397394 DA538092 DQ895947 ABM86873 EU176445 ABW03896 X74796 CAA52803 XM_005250348 XP_005250405 NM_001278595 NP_001265524 NM_005916 NP_005907 NM_182776 NP_877577
Function	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage. {ECO:0000269|PubMed:15210935, ECO:0000269|PubMed:15538388, ECO:0000269|PubMed:9305914}.
Subcellular Location	Nucleus {ECO:0000250}.
Top Pathways	DNA replication, Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MCM7 full length protein - ab114356 from Abcam Category Protein Source Wheat germ Species Human

Human MCM7 protein fragment - ab177663 from Abcam Category Protein Source E. coli Species Human

MCM7 Antibody Blocking Peptide - LS-E4082 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM7 Antibody Blocking Peptide - LS-E13144 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM7 Antibody Blocking Peptide - LS-E13143 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM7 Antibody Blocking Peptide - LS-E13152 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM7 Antibody Blocking Peptide - LS-E13153 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM7 Antibody Blocking Peptide - LS-E13163 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM7 Recombinant Protein - H00004176-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

MCM7-Antibody-N-term-Blocking-Peptide - BP16322a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MCM7 Blocking Peptide - 33R-5458 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MCM7 Blocking Peptide - 33R-3843 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MCM7 Blocking Peptide - 33R-3298 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MCM7 Blocking Peptide - 33R-5687 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MCM7 protein (His tag) - 80R-3657 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

MCM7 (1-414, His-tag) - AR51344PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

MCM7 (1-414, His-tag) - AR51344PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

MCM7 - H00004176-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MCM7 - H00004176-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MCM7, 1-414aa, Human, His tag, E.coli - 01-P2524 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

MCM7 fusion protein - ag1730 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human MCM7 - MCM7-28043TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human MCM7, His-tagged - MCM7-5028H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human minichromosome maintenance complex component 7, His-tagged - MCM7-427H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human DNA replication licensing factor MCM7(MCM7) - CSB-YP013597HU CSB-EP013597HU CSB-BP013597HU CSB-MP013597HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

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