HCRT

Gene Symbol	HCRT
Entrez Gene	3060
Alt Symbol	NRCLP1, OX, PPOX
Species	Human
Gene Type	protein-coding
Description	hypocretin (orexin) neuropeptide precursor
Other Description	orexin|prepro-orexin
Swissprots	O43612
Accessions	AAD24459 EAW60810 O43612 AF041240 AAC39600 BC111915 AAI11916 NM_001524 NP_001515
Function	Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.
Subcellular Location	Rough endoplasmic reticulum {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses. {ECO:0000250}.
Tissue Specificity	Abundantly expressed in subthalamic nucleus but undetectable in other brain regions tested (hypothalamus was not tested) and in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HCRT / Orexin ELISA Kit (Competitive EIA) - LS-F9495 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 12.35 pg/ml Range 12.35-1000 pg/ml

Mouse HCRT / Orexin ELISA Kit (Sandwich ELISA) - LS-F12225 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 7.8 pg/ml Range 12.35-1000 pg/ml

Mouse HCRT / Orexin ELISA Kit (Competitive EIA) - LS-F9496 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 2.94 pg/ml Range 12.35-1000 pg/ml

Human Orexin ELISA Kit - abx152593 from Abbexa Category ELISA Kit Sensitivity 4.25 pg/ml Range 12.35 pg/ml - 1000 pg/ml

Human Orexin ELISA Kit - abx055123 from Abbexa Category ELISA Kit

Orexin (OX), Human, ELISA Kit - CEA346Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 4.22pg/mL Range 12.35-1,000pg/mL

Orexin A, Human, ELISA Kit - CSB-E08859h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

Orexin, HCRT, Human, ELISA Kit - E0777h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 15.6-1000 pg/mL

Anserine Orexin ELISA Kit - AO0328 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Orexin, ELISA Kit - MBS283439 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Orexin (OX), ELISA Kit - MBS2000168 from MyBioSource Category ELISA Kit Prices $345.00, $515.00, $695.00, $2,840.00, $5,180.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 4.92pg/mL. Range 12.35-1000pg/mL

Orexin (OX), ELISA Kit - MBS2000027 from MyBioSource Category ELISA Kit Prices $350.00, $525.00, $715.00, $2,915.00, $5,315.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 2.94pg/mL. Range 6.17-500pg/mL

Orexin A, ELISA Kit - MBS005125 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Orexin A, ELISA Kit - MBS732167 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/mL.

Orexin A, ELISA Kit - MBS040206 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Orexin A, ELISA Kit - MBS722459 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Orexin A, ELISA Kit - MBS015646 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 10pg/ml. Range 62.5 pg/ml - 2000 pg/ml.

Orexin A, ELISA Kit - MBS094243 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Orexin A, ELISA Kit - MBS025383 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Orexin A, ELISA Kit - MBS021290 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.25ng/ml-8ng/ml.

Orexin A, ELISA Kit - MBS735280 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/mL.

Orexin A, ELISA Kit - MBS097086 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Orexin A, ELISA Kit - MBS052291 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Orexin A, ELISA Kit - MBS701515 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.039 ng/ml. Range 0.156 ng/ml-10 ng/ml.

Orexin A, ELISA Kit - MBS036941 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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