MCM2

Gene Symbol	MCM2
Entrez Gene	4171
Alt Symbol	BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19
Species	Human
Gene Type	protein-coding
Description	minichromosome maintenance complex component 2
Other Description	DNA replication licensing factor MCM2|MCM2 minichromosome maintenance deficient 2, mitotin|cell devision cycle-like 1|cyclin-like 1|minichromosome maintenance deficient 2 (mitotin)|minichromosome maintenance protein 2 homolog|nuclear protein BM28
Swissprots	P49736 Q15023 Q96AE1 Q14577 Q9BRM7 Q969W7 Q8N2V1
Accessions	AAT70723 CAR95152 CBX85462 CCD32687 EAW79339 P49736 AK128291 BAG54656 AK299934 BAG61767 AK304204 BAH14132 AK309335 BC000300 AAH00300 BC006165 AAH06165 BC007670 AAH07670 BC007938 AAH07938 BC014272 AAH14272 BC017258 AAH17258 BC017490 AAH17490 BC030131 AAH30131 BM153020 BT009733 AAP88735 BT009734 AAP88736 D21063 BAA04642 D83987 BAA12177 DB100427 X67334 CAA47749 NM_004526 NP_004517 NR_073375
Function	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. {ECO:0000269|PubMed:8175912}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:8175912}.
Top Pathways	DNA replication, Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MCM2 protein fragment - ab92247 from Abcam Category Protein Source E. coli Species Human

CCNL1 / Cyclin L1 Antibody Blocking Peptide - LS-E11697 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CCNL1 / Cyclin L1 Antibody Blocking Peptide - LS-E11698 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM2 Antibody Blocking Peptide - LS-E6464 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM2 Antibody Blocking Peptide - LS-E13139 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM2 Antibody Blocking Peptide - LS-E13138 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM2 Antibody Blocking Peptide - LS-E10094 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CCNL1 Protein - H00057018-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human MCM2 Protein - H00004171-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MCM2-Antibody-C-term-Blocking-Peptide - BP9377b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human MCM2 protein - orb244368 from Biorbyt Category Protein Prices $213.00, $408.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Human

MCM2 Blocking Peptide - 33R-7129 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MCM2 Blocking Peptide - 33R-6804 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MCM2 Blocking Peptide - abx062921 from Abbexa Category Peptide Species Human

MCM2 - H00004171-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MCM2 - H00004171-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MCM2 fusion protein - Ag0798 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human MCM2, His-tagged - MCM2-28039TH from Creative Biomart Category Protein Source E. coli

Recombinant Minichromosome Maintenance Deficient 2 (MCM2) - RPB768Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

MCM2 Blocking Peptide - CBP1727 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

MCM2 / BM28 (A11) Peptide - BS1221P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Minichromosome Maintenance Deficient 2 (MCM2) - RPB768Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human DNA replication licensing factor MCM2(MCM2) ,partial - CSB-YP013590HU CSB-BP013590HU CSB-MP013590HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human DNA replication licensing factor MCM2 - CSB-EP013590HU from Cusabio Category Protein Source E.coli Species Human

MCM2 (770-895) - sc-4424 WB from Santa Cruz Biotechnology Category Protein Prices $88.00 Sizes 10 µg/0.1 ml Species Human

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