MCM2

Gene Symbol	MCM2
Entrez Gene	4171
Alt Symbol	BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19
Species	Human
Gene Type	protein-coding
Description	minichromosome maintenance complex component 2
Other Description	DNA replication licensing factor MCM2|MCM2 minichromosome maintenance deficient 2, mitotin|cell devision cycle-like 1|cyclin-like 1|minichromosome maintenance deficient 2 (mitotin)|minichromosome maintenance protein 2 homolog|nuclear protein BM28
Swissprots	P49736 Q15023 Q96AE1 Q14577 Q9BRM7 Q969W7 Q8N2V1
Accessions	AAT70723 CAR95152 CBX85462 CCD32687 EAW79339 P49736 AK128291 BAG54656 AK299934 BAG61767 AK304204 BAH14132 AK309335 BC000300 AAH00300 BC006165 AAH06165 BC007670 AAH07670 BC007938 AAH07938 BC014272 AAH14272 BC017258 AAH17258 BC017490 AAH17490 BC030131 AAH30131 BM153020 BT009733 AAP88735 BT009734 AAP88736 D21063 BAA04642 D83987 BAA12177 DB100427 X67334 CAA47749 NM_004526 NP_004517 NR_073375
Function	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. {ECO:0000269|PubMed:8175912}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:8175912}.
Top Pathways	DNA replication, Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MCM2 ELISA Kit (Sandwich ELISA) - LS-F4976 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Mouse/Human MCM2 ELISA Kit (Cell-Based ELISA) - LS-F2133 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Rabbit anti-Phospho MCM2 (S40/S41) Antibody, Affinity Purified - PLA0141 from Sigma-Aldrich Prices $345.00 Sizes 100 µl

Rabbit anti-Phospho MCM2 (S108) Antibody, Affinity Purified - PLA0026 from Sigma-Aldrich Prices $345.00 Sizes 100 µl

Rabbit anti-Phospho MCM2 (S27) Antibody, Affinity Purified - PLA0033 from Sigma-Aldrich Prices $345.00 Sizes 100 µl

Rabbit anti-Phospho MCM2 (S53) Antibody, Affinity Purified - PLA0138 from Sigma-Aldrich Prices $345.00 Sizes 100 µl

Rabbit anti-Phospho MCM2 (S41) Antibody, Affinity Purified - PLA0034 from Sigma-Aldrich Prices $345.00 Sizes 100 µl

Goat anti-MCM2 Antibody, Affinity Purified - PLA0037 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

Rabbit anti-MCM2 Antibody, Affinity Purified - PLA0060 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

Human MCM2 ELISA Kit - abx152288 from Abbexa Category ELISA Kit Sensitivity 0.055 ng/ml Range 0.156 ng/ml - 10 ng/ml

Cyclin-L1 (CCNL1), Human, ELISA Kit - E01C1167 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0ng/ml Range 10-250ng/ml

DNA replication licensing factor MCM2, MCM2, Human, ELISA Kit - E1768h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.078-5 ng/mL

Minichromosome Maintenance Deficient 2 (MCM2), Human, ELISA Kit - SEB768Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.058ng/mL Range 0.156-10ng/mL

MCM2 (Human) IP-WB Antibody Pair - H00004171-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

MCM2 (Human) IP-WB Antibody Pair - H00004171-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

MCM2 Colorimetric Cell-Based ELISA Kit - CB5433 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

minichromosome maintenance complex component 2, ELISA Kit - MBS9339069 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Minichromosome Maintenance Deficient 2, ELISA Kit - MBS058409 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Minichromosome Maintenance Deficient 2, ELISA Kit - MBS091694 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Minichromosome Maintenance Deficient 2, ELISA Kit - MBS106041 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Minichromosome Maintenance Deficient 2, ELISA Kit - MBS094534 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Minichromosome Maintenance Deficient 2, ELISA Kit - MBS063569 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Minichromosome Maintenance Deficient 2, ELISA Kit - MBS066648 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Minichromosome Maintenance Deficient 2, ELISA Kit - MBS096879 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Minichromosome Maintenance Deficient 2, ELISA Kit - MBS090752 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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