MCM2

Gene Symbol MCM2
Entrez Gene 4171
Alt Symbol BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19
Species Human
Gene Type protein-coding
Description minichromosome maintenance complex component 2
Other Description DNA replication licensing factor MCM2|MCM2 minichromosome maintenance deficient 2, mitotin|cell devision cycle-like 1|cyclin-like 1|minichromosome maintenance deficient 2 (mitotin)|minichromosome maintenance protein 2 homolog|nuclear protein BM28
Swissprots P49736 Q15023 Q96AE1 Q14577 Q9BRM7 Q969W7 Q8N2V1
Accessions AAT70723 CAR95152 CBX85462 CCD32687 EAW79339 P49736 AK128291 BAG54656 AK299934 BAG61767 AK304204 BAH14132 AK309335 BC000300 AAH00300 BC006165 AAH06165 BC007670 AAH07670 BC007938 AAH07938 BC014272 AAH14272 BC017258 AAH17258 BC017490 AAH17490 BC030131 AAH30131 BM153020 BT009733 AAP88735 BT009734 AAP88736 D21063 BAA04642 D83987 BAA12177 DB100427 X67334 CAA47749 NM_004526 NP_004517 NR_073375
Function Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. {ECO:0000269|PubMed:8175912}.
Subcellular Location Nucleus {ECO:0000269|PubMed:8175912}.
Top Pathways DNA replication, Cell cycle

MCM2 CRISPR/Cas9 KO Plasmid (h) - sc-400959 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM2 HDR Plasmid (h) - sc-400959-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM2 Double Nickase Plasmid (h) - sc-400959-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM2 Double Nickase Plasmid (h2) - sc-400959-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM2 CRISPR Activation Plasmid (h) - sc-400959-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM2 CRISPR Activation Plasmid (h2) - sc-400959-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM2 Lentiviral Activation Particles (h) - sc-400959-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM2 Lentiviral Activation Particles (h2) - sc-400959-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM2 siRNA (h) - sc-35879 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCM2 shRNA Plasmid (h) - sc-35879-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCM2 shRNA (h) Lentiviral Particles - sc-35879-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CCNL1 RNAi - H00057018-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU144341 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13117 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05608 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05608

MCM2 siRNA (Human) - CRH2839 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MCM2 RNAi - H00004171-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MCM2 CRISPR/Cas9 KO Plasmid (h2) - sc-400959-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM2 HDR Plasmid (h2) - sc-400959-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human MCM2 (NM_004526.3) - SHH339275 from Creative biogene

Category siRNA
Species Reactivities Human

Human MCM2 siRNA - orb263341 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MCM2 shRNA Plasmid (Human) - CHH2839 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MCM2 miRNA 3'UTR clone - MiUTR3H-00391 from Creative biogene

Species Reactivities Human
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