SFRP5

Gene Symbol SFRP5
Entrez Gene 6425
Alt Symbol SARP3
Species Human
Gene Type protein-coding
Description secreted frizzled-related protein 5
Other Description FRP-1b|SARP-3|frizzled-related protein 1b|sFRP-5|secreted apoptosis related protein 3|secreted apoptosis-related protein 3
Swissprots Q86TH7 Q5T4F7 O14780
Accessions EAW49894 Q5T4F7 AF017988 AAB70794 AF117758 AAD25052 BC050435 AAH50435 NM_003015 NP_003006
Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina.
Subcellular Location Secreted {ECO:0000250}.
Tissue Specificity Highly expressed in the retinal pigment epithelium (RPE) and pancreas. Weak expression in heart, liver and muscle. {ECO:0000269|PubMed:10072424, ECO:0000269|PubMed:9391078, ECO:0000269|PubMed:9642118}.
Top Pathways Wnt signaling pathway

Human sFRP5 gene - orb91246 from Biorbyt

Prices $255.00
Sizes 10 μg
Species Human

human SFRP5 ORF clone - CDCH079266 from Creative Biomart

Species Human
Accession NM_003015

human SFRP5 ORF clone - CDCH079267 from Creative Biomart

Species Human
Accession NM_003015

human SFRP5 ORF clone - CDCH079268 from Creative Biomart

Species Human
Accession NM_003015

human SFRP5 ORF clone - CDCH079269 from Creative Biomart

Species Human
Accession NM_003015
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