SFRP5

Gene Symbol SFRP5
Entrez Gene 6425
Alt Symbol SARP3
Species Human
Gene Type protein-coding
Description secreted frizzled-related protein 5
Other Description FRP-1b|SARP-3|frizzled-related protein 1b|sFRP-5|secreted apoptosis related protein 3|secreted apoptosis-related protein 3
Swissprots Q86TH7 Q5T4F7 O14780
Accessions EAW49894 Q5T4F7 AF017988 AAB70794 AF117758 AAD25052 BC050435 AAH50435 NM_003015 NP_003006
Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina.
Subcellular Location Secreted {ECO:0000250}.
Tissue Specificity Highly expressed in the retinal pigment epithelium (RPE) and pancreas. Weak expression in heart, liver and muscle. {ECO:0000269|PubMed:10072424, ECO:0000269|PubMed:9391078, ECO:0000269|PubMed:9642118}.
Top Pathways Wnt signaling pathway

SARP3 CRISPR/Cas9 KO Plasmid (h) - sc-402848 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SARP3 HDR Plasmid (h) - sc-402848-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SARP3 Double Nickase Plasmid (h) - sc-402848-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SARP3 Double Nickase Plasmid (h2) - sc-402848-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SARP3 CRISPR Activation Plasmid (h) - sc-402848-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SARP3 CRISPR Activation Plasmid (h2) - sc-402848-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SARP3 Lentiviral Activation Particles (h) - sc-402848-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SARP3 Lentiviral Activation Particles (h2) - sc-402848-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SARP3 siRNA (h) - sc-40004 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SARP3 shRNA Plasmid (h) - sc-40004-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SARP3 shRNA (h) Lentiviral Particles - sc-40004-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU055561 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN19199 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19199 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06355 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06355

SFRP5 siRNA (Human) - CRH4340 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SFRP5 - MBS8237861 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SFRP5 shRNA Plasmid (Human) - CHH4340 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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