ELMO1

Gene Symbol ELMO1
Entrez Gene 9844
Alt Symbol CED-12, CED12, ELMO-1
Species Human
Gene Type protein-coding
Description engulfment and cell motility 1
Other Description ced-12 homolog 1|engulfment and cell motility protein 1
Swissprots Q9H0I1 A4D1X6 Q96PB0 Q6ZTJ0 Q29R79 Q92556
Accessions EAL23978 EAL23979 EAW94075 EAW94076 EAW94077 EAW94078 EAW94079 Q92556 AF398885 AAL14466 AK001084 AK126565 BAC86597 AK291784 BAF84473 AK296253 BAG58968 AK301151 BAG62742 AK314349 AL136787 CAB66721 BC003051 AAH03051 BC064635 AAH64635 BC077074 AAH77074 BC114341 AAI14342 BI600726 D87457 BAA13397 DA238090 DA312397 DB156714 DC366992 HQ448196 ADQ32677 XM_005249919 XP_005249976 XM_006715805 XP_006715868 XM_011515654 XP_011513956 XM_011515655 XP_011513957 NM_001039459 NP_001034548 NM_001206480 NP_001193409 NM_001206482 NP_001193411 NM_014800 NP_055615 NM_130442 NP_569709 NR_038120
Function Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. {ECO:0000269|PubMed:11595183, ECO:0000269|PubMed:12134158}.
Subcellular Location Cytoplasm. Cell membrane. Note=Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
Tissue Specificity Widely expressed, with a higher expression in the spleen and placenta.
Top Pathways Chemokine signaling pathway, Bacterial invasion of epithelial cells

ELMO1 (D4K2E) Rabbit mAb - 14457 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4K2E
Western blot analysis of extracts from various cell lines using ELMO1 (D4K2E) Rabbit mAb (upper) or α-Actinin (D6F6) XP ® Rabbit mAb #6487 (lower).

Elmo (G-8) - sc-166555 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Elmo (G-8): sc-166555. Western blot analysis of Elmo expression in Jurkat (A) and RAW 264.7 (B) whole cell lysates.

Elmo (T-20) - sc-31904 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Elmo (FL-727) - sc-20965 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Elmo (FL-727): sc-20965. Western blot analysis of Elmo expression in MOLT-4 (A) and Jurkat (B) whole cell lysates.

Elmo (D-18) - sc-31905 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Elmo (D-18): sc-31905. Immunoperoxidase staining of formalin fixed, paraffin-embedded human upper stomach tissue showing cytoplasmic staining of glandular cells.

Elmo1 (B-7) - sc-271519 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Elmo1 (B-7): sc-271519. Western blot analysis of Elmo1 expression in Jurkat (A) and MOLT-4 (B) whole cell lysates.

Elmo1 (C-3) - sc-166661 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Elmo1 (C-3): sc-166661. Western blot analysis of Elmo1 expression in non-transfected 293T: sc-117752 (A), mouse Elmo1 transfected 293T: sc-120003 (B), MOLT-4 (C) and Jurkat (D) whole cell lysates.

Elmo1 (E-15) - sc-21652 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Elmo1 (E-15): sc-21652. Western blot analysis of Elmo1 expression in Jurkat whole cell lysate.

Elmo1 (N-20) - sc-21651 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Elmo1 (N-20): sc-21651. Western blot analysis of Elmo1 expression in Jurkat (A) and MOLT-4 (B) whole cell lysates.

Anti-ELMO1 antibody - ab169426 from Abcam

Host Mouse
Clonality Polyclonal
All lanes : Anti-ELMO1 antibody (ab169426) at 1 µg/mlLane 1 : ELMO1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-ELMO1 antibody - ab135850 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ELMO1 antibody (ab135850) at 1/500 dilution + Jurkat cell extracts at 30 µg

Anti-ELMO1 antibody [EPR12919] - ab174298 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12919
Western blot analysis on immunoprecipitation pellet from Jurkat cell lysate immunoprecipitated using ab174298 at 1/10 dilution.

Anti-ELMO1 / ELMO 1 Antibody (Internal, AP) - LS-C277078 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELMO1 / ELMO 1 Antibody (Internal, APC) - LS-C277079 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELMO1 / ELMO 1 Antibody (Internal, Biotin) - LS-C277081 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELMO1 / ELMO 1 Antibody (Internal, FITC) - LS-C277082 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELMO1 / ELMO 1 Antibody (Internal, PE) - LS-C277083 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELMO1 / ELMO 1 Antibody - LS-C307388 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ELMO1 / ELMO 1 Antibody (Internal, Azide-free, HRP) - LS-C277084 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELMO1 / ELMO 1 Antibody (Internal) - LS-C330419 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELMO1 / ELMO 1 Antibody (aa81-126) - LS-C313751 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ELMO1 / ELMO 1 Antibody (aa22-71) - LS-C199842 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from Jurkat cells, using Elmo1 antibody.

Anti-ELMO1 / ELMO 1 Antibody (aa372-421) - LS-C135573 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ELMO1 antibody LS-C135573 Western blot of HepG2 cell lysate.

Anti-ELMO1 / ELMO 1 Antibody (aa714-727) - LS-C54767 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody staining (1 ug/ml) of Jurkat lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

ELMO1 Antibody - NBP1-33645 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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