ELMO1

Gene Symbol ELMO1
Entrez Gene 9844
Alt Symbol CED-12, CED12, ELMO-1
Species Human
Gene Type protein-coding
Description engulfment and cell motility 1
Other Description ced-12 homolog 1|engulfment and cell motility protein 1
Swissprots Q9H0I1 A4D1X6 Q96PB0 Q6ZTJ0 Q29R79 Q92556
Accessions EAL23978 EAL23979 EAW94075 EAW94076 EAW94077 EAW94078 EAW94079 Q92556 AF398885 AAL14466 AK001084 AK126565 BAC86597 AK291784 BAF84473 AK296253 BAG58968 AK301151 BAG62742 AK314349 AL136787 CAB66721 BC003051 AAH03051 BC064635 AAH64635 BC077074 AAH77074 BC114341 AAI14342 BI600726 D87457 BAA13397 DA238090 DA312397 DB156714 DC366992 HQ448196 ADQ32677 XM_005249919 XP_005249976 XM_006715805 XP_006715868 XM_011515654 XP_011513956 XM_011515655 XP_011513957 NM_001039459 NP_001034548 NM_001206480 NP_001193409 NM_001206482 NP_001193411 NM_014800 NP_055615 NM_130442 NP_569709 NR_038120
Function Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. {ECO:0000269|PubMed:11595183, ECO:0000269|PubMed:12134158}.
Subcellular Location Cytoplasm. Cell membrane. Note=Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
Tissue Specificity Widely expressed, with a higher expression in the spleen and placenta.
Top Pathways Chemokine signaling pathway, Bacterial invasion of epithelial cells

ELMO1-Over-expression-Lysate - LY11974a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag ELMO1 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ELMO1 gene

ELMO1 Lysate(Denatured) - H00009844-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

ELMO1 overexpression lysate - LY403326 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

ELMO1 overexpression lysate - LY422048 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

ELMO1 293 Cell Lysate - 402886 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

ELMO1 293 Cell Lysate - 409623 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

ELMO1 Overexpression Lysate (Denatured) - H00009844-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

ELMO1 Overexpression Lysate (Native) - NBL1-10239 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: ELMO1 Overexpression Lysate (Adult Normal) [NBL1-10239] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ELMO1.

ELMO1 Overexpression Lysate (Native) - NBP2-08572 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

ELMO1 Overexpression Lysate (Native) - NBP2-07272 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: ELMO1 Overexpression Lysate (Adult Normal) [NBP2-07272] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ELMO1.

ELMO1 Over-expression Lysate Product - GWB-D751A7 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

ELMO1 Over-expression Lysate Product - GWB-A6BEDC from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

ELMO1 Overexpression Lysate (Native) - NBP2-09868 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: ELMO1 Overexpression Lysate (Adult Normal) [NBP2-09868] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ELMO1.

Panoply™ Human ELMO1 Knockdown Stable Cell Line - CSC-DC004866 from Creative biogene

Category Cell Line
Species Human
Search more