ELMO1

Gene Symbol ELMO1
Entrez Gene 9844
Alt Symbol CED-12, CED12, ELMO-1
Species Human
Gene Type protein-coding
Description engulfment and cell motility 1
Other Description ced-12 homolog 1|engulfment and cell motility protein 1
Swissprots Q9H0I1 A4D1X6 Q96PB0 Q6ZTJ0 Q29R79 Q92556
Accessions EAL23978 EAL23979 EAW94075 EAW94076 EAW94077 EAW94078 EAW94079 Q92556 AF398885 AAL14466 AK001084 AK126565 BAC86597 AK291784 BAF84473 AK296253 BAG58968 AK301151 BAG62742 AK314349 AL136787 CAB66721 BC003051 AAH03051 BC064635 AAH64635 BC077074 AAH77074 BC114341 AAI14342 BI600726 D87457 BAA13397 DA238090 DA312397 DB156714 DC366992 HQ448196 ADQ32677 XM_005249919 XP_005249976 XM_006715805 XP_006715868 XM_011515654 XP_011513956 XM_011515655 XP_011513957 NM_001039459 NP_001034548 NM_001206480 NP_001193409 NM_001206482 NP_001193411 NM_014800 NP_055615 NM_130442 NP_569709 NR_038120
Function Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. {ECO:0000269|PubMed:11595183, ECO:0000269|PubMed:12134158}.
Subcellular Location Cytoplasm. Cell membrane. Note=Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
Tissue Specificity Widely expressed, with a higher expression in the spleen and placenta.
Top Pathways Chemokine signaling pathway, Bacterial invasion of epithelial cells

Elmo1 CRISPR/Cas9 KO Plasmid (h) - sc-417055 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo1 HDR Plasmid (h) - sc-417055-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo1 Double Nickase Plasmid (h) - sc-417055-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo1 Double Nickase Plasmid (h2) - sc-417055-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo1 CRISPR Activation Plasmid (h) - sc-417055-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo1 CRISPR Activation Plasmid (h2) - sc-417055-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo1 Lentiviral Activation Particles (h) - sc-417055-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo1 Lentiviral Activation Particles (h2) - sc-417055-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo1 siRNA (h) - sc-40525 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Elmo1 shRNA Plasmid (h) - sc-40525-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Elmo1 shRNA (h) Lentiviral Particles - sc-40525-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU087981 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7812 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7812 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08670 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08670

ELMO1 siRNA (Human) - CRH6596 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ELMO1 - MBS829403 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human ELMO1 siRNA - orb267098 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ELMO1 shRNA Plasmid (Human) - CHH6596 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ELMO1 miRNA 3'UTR clone - MiUTR3H-08436 from Creative biogene

Species Reactivities Human

ELMO1 miRNA 3'UTR clone - MiUTR3H-08437 from Creative biogene

Species Reactivities Human
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