Gene Symbol | ELMO1 |
---|---|
Entrez Gene | 9844 |
Alt Symbol | CED-12, CED12, ELMO-1 |
Species | Human |
Gene Type | protein-coding |
Description | engulfment and cell motility 1 |
Other Description | ced-12 homolog 1|engulfment and cell motility protein 1 |
Swissprots | Q9H0I1 A4D1X6 Q96PB0 Q6ZTJ0 Q29R79 Q92556 |
Accessions | EAL23978 EAL23979 EAW94075 EAW94076 EAW94077 EAW94078 EAW94079 Q92556 AF398885 AAL14466 AK001084 AK126565 BAC86597 AK291784 BAF84473 AK296253 BAG58968 AK301151 BAG62742 AK314349 AL136787 CAB66721 BC003051 AAH03051 BC064635 AAH64635 BC077074 AAH77074 BC114341 AAI14342 BI600726 D87457 BAA13397 DA238090 DA312397 DB156714 DC366992 HQ448196 ADQ32677 XM_005249919 XP_005249976 XM_006715805 XP_006715868 XM_011515654 XP_011513956 XM_011515655 XP_011513957 NM_001039459 NP_001034548 NM_001206480 NP_001193409 NM_001206482 NP_001193411 NM_014800 NP_055615 NM_130442 NP_569709 NR_038120 |
Function | Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. {ECO:0000269|PubMed:11595183, ECO:0000269|PubMed:12134158}. |
Subcellular Location | Cytoplasm. Cell membrane. Note=Translocation to plasma membrane seems to be mediated by DOCK1 and CRK. |
Tissue Specificity | Widely expressed, with a higher expression in the spleen and placenta. |
Top Pathways | Chemokine signaling pathway, Bacterial invasion of epithelial cells |
Human ELMO1 full length protein - ab131839 from Abcam
|
||||||||||
Human ELMO1 peptide - ab72858 from Abcam
|
||||||||||
Human ELMO1 peptide - ab22878 from Abcam
|
||||||||||
Human ELMO1 protein fragment - ab153021 from Abcam
|
||||||||||
ELMO1 / ELMO 1 Antibody Blocking Peptide - LS-E25294 from LifeSpan Bioscience
|
||||||||||
ELMO1 / ELMO 1 Antibody Blocking Peptide - LS-E21820 from LifeSpan Bioscience
|
||||||||||
ELMO1 / ELMO 1 Blocking Peptide - LS-E9763 from LifeSpan Bioscience
|
||||||||||
Recombinant Human ELMO1 Protein - H00009844-P01 from Novus Biologicals
|
||||||||||
ELMO1 Partial Recombinant Protein - H00009844-Q01 from Novus Biologicals
|
||||||||||
ELMO1-Antibody-Center-Blocking-Peptide - BP8761c from Abgent, a WuXi AppTec company
|
||||||||||
ELMO1 blocking peptide - GTX89955-PEP from GeneTex
|
||||||||||
Goat anti ELMO1 antibody Immunizing peptide - orb17622 from Biorbyt
|
||||||||||
ELMO1 Blocking Peptide - 33R-9254 from Fitzgerald
|
||||||||||
ELMO1 Blocking Peptide - abx063621 from Abbexa
|
||||||||||
ELMO1 Peptide - AC21-0122-P from Abcore
|
||||||||||
ELMO1 - H00009844-P01-10 from Acris Antibodies
|
||||||||||
ELMO1 - H00009844-P01-25 from Acris Antibodies
|
||||||||||
ELMO1 - H00009844-Q01-10 from Acris Antibodies
|
||||||||||
ELMO1 - H00009844-Q01-25 from Acris Antibodies
|
||||||||||
ELMO1 Peptide - 45-530P from ProSci
|
||||||||||
ELMO1 Blocking Peptide - CBP2427 from Cohesion Biosciences
|
||||||||||
ELMO1 Peptide - BS5711P from Bioworld Technology
|
||||||||||
Recombinant Human Engulfment and cell motility protein 1(ELMO1) - CSB-YP856404HU CSB-EP856404HU CSB-BP856404HU CSB-MP856404HU from Cusabio
|
||||||||||
ELMO1 (transcript variant 1) - TP315541 from Acris Antibodies
|
||||||||||
ELMO1 (transcript variant 3) - TP315722 from Acris Antibodies
|