ELMO1

Gene Symbol	ELMO1
Entrez Gene	9844
Alt Symbol	CED-12, CED12, ELMO-1
Species	Human
Gene Type	protein-coding
Description	engulfment and cell motility 1
Other Description	ced-12 homolog 1|engulfment and cell motility protein 1
Swissprots	Q9H0I1 A4D1X6 Q96PB0 Q6ZTJ0 Q29R79 Q92556
Accessions	EAL23978 EAL23979 EAW94075 EAW94076 EAW94077 EAW94078 EAW94079 Q92556 AF398885 AAL14466 AK001084 AK126565 BAC86597 AK291784 BAF84473 AK296253 BAG58968 AK301151 BAG62742 AK314349 AL136787 CAB66721 BC003051 AAH03051 BC064635 AAH64635 BC077074 AAH77074 BC114341 AAI14342 BI600726 D87457 BAA13397 DA238090 DA312397 DB156714 DC366992 HQ448196 ADQ32677 XM_005249919 XP_005249976 XM_006715805 XP_006715868 XM_011515654 XP_011513956 XM_011515655 XP_011513957 NM_001039459 NP_001034548 NM_001206480 NP_001193409 NM_001206482 NP_001193411 NM_014800 NP_055615 NM_130442 NP_569709 NR_038120
Function	Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. {ECO:0000269|PubMed:11595183, ECO:0000269|PubMed:12134158}.
Subcellular Location	Cytoplasm. Cell membrane. Note=Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
Tissue Specificity	Widely expressed, with a higher expression in the spleen and placenta.
Top Pathways	Chemokine signaling pathway, Bacterial invasion of epithelial cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-ELMO1-cDNA-Clone - DC01217 from Abgent, a WuXi AppTec company Prices $333.45 Sizes 10 µg Species Human Accession BC003051

ELMO1 - MBS1277063 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC114341

ELMO1 - MBS1271251 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC003051

Human ELMO1 ORF Clone(NM_014800.10) - CDCL162255 from Creative Biomart Species Human Accession NM_014800.10

Human ELMO1 ORF Clone(NM_001039459.2) - CDCL162256 from Creative Biomart Species Human Accession NM_001039459.2

Human ELMO1 Gene ORF cDNA clone in cloning vector - HG16005-G from Sino Biological Species Human

Human ELMO1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG16005-NY from Sino Biological Species Human

Human ELMO1 Gene ORF cDNA clone expression plasmid, N-His tag - HG16005-NH from Sino Biological Species Human

Human ELMO1 Gene ORF cDNA clone expression plasmid, C-His tag - HG16005-CH from Sino Biological Species Human

Human ELMO1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG16005-NF from Sino Biological Species Human

Human ELMO1 Gene ORF cDNA clone expression plasmid - HG16005-UT from Sino Biological Species Human

Human ELMO1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG16005-CF from Sino Biological Species Human

Human ELMO1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG16005-NM from Sino Biological Species Human

Human ELMO1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG16005-CM from Sino Biological Species Human

Human ELMO1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG16005-CY from Sino Biological Species Human

Human ELMO1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG16005-ACG from Sino Biological Species Human

Human ELMO1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG16005-ACR from Sino Biological Species Human

Human ELMO1 ORF clone (NM_001039459.2) - CDCR059910 from Creative biogene Species Human

Human ELMO1 ORF Clone (BC003051) - CDCS406949 from Creative biogene Species Human Accession Q92556

Human ELMO1 ORF Clone (BC114341) - CDCS406950 from Creative biogene Species Human Accession Q92556

Human ELMO1 ORF clone (BC114341) - CDCB157580 from Creative biogene Species Human

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