NKX2-1

Gene Symbol	NKX2-1
Entrez Gene	7080
Alt Symbol	BCH, BHC, NK-2, NKX2.1, NKX2A, T/EBP, TEBP, TITF1, TTF-1, TTF1
Species	Human
Gene Type	protein-coding
Description	NK2 homeobox 1
Other Description	NK-2 homolog A|homeobox protein NK-2 homolog A|homeobox protein Nkx-2.1|thyroid nuclear factor 1|thyroid transcription factor 1|thyroid-specific enhancer-binding protein
Swissprots	P43699 O14954 Q9BRJ8 Q7KZF6 O14955 D3DSA3
Accessions	AAA83233 AAC12924 AAC50125 BAA23527 BAB56137 EAW65856 EAW65857 EAW65858 EAW65859 P43699 BC006221 AAH06221 BE796718 BM970287 BM970838 BT009773 AAP88775 D50740 BAA23529 D50741 BAA23528 DQ892964 ABM83890 DQ896211 ABM87210 U19756 AAA86099 U33749 AAB52381 U43203 AAA89066 X82850 CAA58053 NM_001079668 NP_001073136 NM_003317 NP_003308
Function	Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity). {ECO:0000250|UniProtKB:P23441, ECO:0000250|UniProtKB:P50220}.
Subcellular Location	Nucleus {ECO:0000250|UniProtKB:P50220}.
Tissue Specificity	Thyroid and lung.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TITF1 293T Cell Transient Overexpression Lysate(Denatured) - H00007080-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

NKX2 overexpression lysate - LY401141 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

NKX2 overexpression lysate - LY421530 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

NKX2 overexpression lysate - LY425889 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

NKX2 293 Cell Lysate - 401060 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

TTF1 / NKX2.1 Overexpression Lysate (Denatured) - H00007080-T01 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl Species Human

TTF1 / NKX2.1 Overexpression Lysate (Native) - NBL1-13658 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TTF-1 (h2): 293T Lysate - sc-159187 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

NKX2 Over-expression Lysate Product - GWB-11C90D from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

TTF1 / NKX2.1 Overexpression Lysate (Native) - NBP2-11446 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TTF1 / NKX2.1 Overexpression Lysate (Native) - NBP2-10635 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human NKX2-1 Knockdown Stable Cell Line - CSC-DC010409 from Creative biogene Category Cell Line Species Human

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