NKX2-1

Gene Symbol	NKX2-1
Entrez Gene	7080
Alt Symbol	BCH, BHC, NK-2, NKX2.1, NKX2A, T/EBP, TEBP, TITF1, TTF-1, TTF1
Species	Human
Gene Type	protein-coding
Description	NK2 homeobox 1
Other Description	NK-2 homolog A|homeobox protein NK-2 homolog A|homeobox protein Nkx-2.1|thyroid nuclear factor 1|thyroid transcription factor 1|thyroid-specific enhancer-binding protein
Swissprots	P43699 O14954 Q9BRJ8 Q7KZF6 O14955 D3DSA3
Accessions	AAA83233 AAC12924 AAC50125 BAA23527 BAB56137 EAW65856 EAW65857 EAW65858 EAW65859 P43699 BC006221 AAH06221 BE796718 BM970287 BM970838 BT009773 AAP88775 D50740 BAA23529 D50741 BAA23528 DQ892964 ABM83890 DQ896211 ABM87210 U19756 AAA86099 U33749 AAB52381 U43203 AAA89066 X82850 CAA58053 NM_001079668 NP_001073136 NM_003317 NP_003308
Function	Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity). {ECO:0000250|UniProtKB:P23441, ECO:0000250|UniProtKB:P50220}.
Subcellular Location	Nucleus {ECO:0000250|UniProtKB:P50220}.
Tissue Specificity	Thyroid and lung.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TTF1 full length protein - ab159708 from Abcam Category Protein Source Wheat germ Species Human

Human TTF1 protein fragment - ab159709 from Abcam Category Protein Source Wheat germ Species Human

TTF1 peptide - ab187893 from Abcam Category Peptide

Recombinant Human TTF1 / NKX2.1 Protein - H00007080-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human TTF1 / NKX2.1 Protein - H00007080-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NKX2-1-Antibody-N-term-Blocking-peptide - BP10734a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NKX2-1-Antibody-Center-Blocking-Peptide - BP17825c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CHN2 blocking peptide - GTX88448-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Bovine

NKX2.1 blocking peptide - GTX89117-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

NKX2-1 Blocking Peptide - abx063362 from Abbexa Category Peptide Species Human, Mouse, Rat, Dog, Pig, Sheep, Zebrafish

TTF1 / NKX2A - H00007080-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

TTF1 / NKX2A - H00007080-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TTF1 / NKX2A - H00007080-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TTF1 / NKX2A (N-term) Control Peptide - AP55625CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

NKX2-1 Peptide - 6741P from ProSci Category Peptide Species Human

NKX2-1 fusion protein - ag17414 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human NK2 Homeobox 1 - NKX2-1-226H from Creative Biomart Category Protein Source Recombinant human TTF-1 protein encoding 138-286 amino acids expressed in E.coli .

Recombinant Thyroid Transcription Factor 1 (TITF1) - RPG782Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

NKX2-1 Blocking Peptide - CBP2168 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Dog, Pig, Sheep, Zebrafish

Recombinant Human Homeobox protein Nkx-2.1(NKX2-1) - CSB-YP015841HU CSB-EP015841HU CSB-BP015841HU CSB-MP015841HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NKX2-1 Peptide, Human - M34GP10409H from Creative Peptides Category Peptide Source Synthetic. Species Human

Homeobox protein Nkx-2.1 (NKX2-1), Recombinant Protein - MBS948649 from MyBioSource Category Protein Prices $1,140.00, $1,140.00, $1,370.00, $1,370.00, $1,815.00, $1,815.00, $2,280.00, $2,280.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

NKX2-1 peptide - orb218031 from Biorbyt Category Peptide Species Human, Mouse, Rat, Zebrafish, Dog, Sheep

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