CLK3

Gene Symbol	CLK3
Entrez Gene	1198
Alt Symbol	PHCLK3, PHCLK3/152
Species	Human
Gene Type	protein-coding
Description	CDC-like kinase 3
Other Description	dual specificity protein kinase CLK3
Swissprots	Q9BUJ7 D3DW59 Q53Y48 Q9BRS3 P49761
Accessions	EAW99320 EAW99321 EAW99322 EAW99323 EAW99324 EAW99325 P49761 AB209535 BAD92772 AK026511 AK091692 BAG52400 AK095335 AK096115 BAG53214 AK097982 BAG53559 AK122860 BAG53765 AK225680 AK291983 BAF84672 AK293769 BAG57185 AK301689 BAG63161 AL833165 BC002555 AAH02555 BC006103 AAH06103 BC009857 BC019881 AAH19881 BI459843 BM678884 BQ183959 BT006993 AAP35639 CR933693 JF432199 ADZ15416 L29217 AAA61484 L29220 AAA61483 XM_005254151 XP_005254208 XM_005254153 XP_005254210 XM_006720384 XP_006720447 XM_011521205 XP_011519507 XM_011521206 XP_011519508 XM_011521207 XP_011519509 XM_011521208 XP_011519510 XM_011521209 XP_011519511 XM_011521210 XP_011519512 XR_931746 NM_001130028 NP_001123500 NM_003992 NP_003983 NM_001292
Function	Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. {ECO:0000269|PubMed:19168442, ECO:0000269|PubMed:9637771}.
Subcellular Location	Isoform 1: Nucleus. Cytoplasm {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}.
Tissue Specificity	Endothelial cells. {ECO:0000269|PubMed:19168442}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-CLK3-cDNA-Clone - DC01866 from Abgent, a WuXi AppTec company Prices $661.50 Sizes 10 µg Species Human Accession BC019881

CLK3 - MBS1275918 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC006103

CLK3 - MBS1276771 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC002555

CLK3 - MBS1272987 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC019881

Human CLK3 cDNA clone(NM_001130028.1) - CDFH003866 from Creative Biomart Species Human Accession NM_001130028.1

Human CLK3 ORF clone(NM_003992.4) - CDCL183626 from Creative Biomart Species Human Accession NM_003992.4

Human CLK3 ORF Clone(NM_001130028.1) - CDCR349365 from Creative Biomart Species Human Accession NM_001130028.1

Human CLK3 ORF Clone(NM_001130028.1) - CDCR349370 from Creative Biomart Species Human Accession NM_001130028.1

Human CLK3 ORF Clone(NM_003992.4) - CDCL159102 from Creative Biomart Species Human Accession NM_003992.4

Human CLK3 Gene ORF cDNA clone in cloning vector - HG10716-U from Sino Biological Species Human

Human CLK3 Gene ORF cDNA clone expression plasmid, C-His tag - HG10716-CH from Sino Biological Species Human

Human CLK3 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10716-ANG from Sino Biological Species Human

Human CLK3 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10716-ACR from Sino Biological Species Human

Human CLK3 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10716-ANR from Sino Biological Species Human

Human CLK3 Gene ORF cDNA clone expression plasmid - HG10716-UT from Sino Biological Species Human

Human CLK3 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10716-ACG from Sino Biological Species Human

Human CLK3 Gene ORF cDNA clone expression plasmid, N-His tag - HG10716-NH from Sino Biological Species Human

Human CLK3 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10716-NF from Sino Biological Species Human

Human CLK3 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10716-NM from Sino Biological Species Human

Human CLK3 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10716-CF from Sino Biological Species Human

Human CLK3 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10716-CY from Sino Biological Species Human

Human CLK3 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10716-CM from Sino Biological Species Human

Human CLK3 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10716-NY from Sino Biological Species Human

Human CLK3 ORF clone(NM_003992.4) - CDCL183626 from Creative biogene Species Human

Human CLK3 ORF clone (NM_001130028.1) - CDCR048202 from Creative biogene Species Human

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