CLK3

Gene Symbol	CLK3
Entrez Gene	1198
Alt Symbol	PHCLK3, PHCLK3/152
Species	Human
Gene Type	protein-coding
Description	CDC-like kinase 3
Other Description	dual specificity protein kinase CLK3
Swissprots	Q9BUJ7 D3DW59 Q53Y48 Q9BRS3 P49761
Accessions	EAW99320 EAW99321 EAW99322 EAW99323 EAW99324 EAW99325 P49761 AB209535 BAD92772 AK026511 AK091692 BAG52400 AK095335 AK096115 BAG53214 AK097982 BAG53559 AK122860 BAG53765 AK225680 AK291983 BAF84672 AK293769 BAG57185 AK301689 BAG63161 AL833165 BC002555 AAH02555 BC006103 AAH06103 BC009857 BC019881 AAH19881 BI459843 BM678884 BQ183959 BT006993 AAP35639 CR933693 JF432199 ADZ15416 L29217 AAA61484 L29220 AAA61483 XM_005254151 XP_005254208 XM_005254153 XP_005254210 XM_006720384 XP_006720447 XM_011521205 XP_011519507 XM_011521206 XP_011519508 XM_011521207 XP_011519509 XM_011521208 XP_011519510 XM_011521209 XP_011519511 XM_011521210 XP_011519512 XR_931746 NM_001130028 NP_001123500 NM_003992 NP_003983 NM_001292
Function	Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. {ECO:0000269|PubMed:19168442, ECO:0000269|PubMed:9637771}.
Subcellular Location	Isoform 1: Nucleus. Cytoplasm {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}.
Tissue Specificity	Endothelial cells. {ECO:0000269|PubMed:19168442}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human CLK3 full length protein - ab85759 from Abcam Category Protein Prices $302.00, $352.00 Sizes 5 µg, 10 µg Source Baculovirus infected sf9 cells Species Human

Human CLK3 full length protein - ab158139 from Abcam Category Protein Source Wheat germ Species Human

Human CLK3 protein fragment - ab158140 from Abcam Category Protein Source Wheat germ Species Human

CLK3 Antibody Blocking Peptide - LS-E3743 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CLK3 Protein - H00001198-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human CLK3 Protein - H00001198-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CLK3 Recombinant Protein - P4670 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 100 µg Species Human

CLK3 - H00001198-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CLK3 - H00001198-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CLK3 - H00001198-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CLK3 - H00001198-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CLK3 - P4670 from Acris Antibodies Category Protein Prices $1,380.00 Sizes 100 µg Species Human

CLK3 - P5694 from Acris Antibodies Category Protein Prices $840.00 Sizes 5 µg Species Human

CLK3 fusion protein - ag0377 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human CDC-like Kinase 3, GST-tagged, Active - CLK3-286H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus .

Recombinant Human CLK3, GST tagged - CLK3-779H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human CLK3 - CLK3-27275TH from Creative Biomart Category Protein

CLK3 - PN201360 from Elabscience Category Protein Prices $225.00, $475.00 Sizes 10 μg, 50 μg Source Insect cells Species Human

CLK3 Protein, active, 250 µg - 14-724M from EMD Millipore Category Protein Prices $2,441.00 Sizes 250 µg also available in 10 μg size . (cat#14-724) and in bulk (cat#14-724-K) Source expressed by baculovirus in Sf21 cells

CLK3 Protein, active, 10 µg - 14-724 from EMD Millipore Category Protein Prices $318.00 Sizes 10 µg Source expressed by baculovirus in Sf21 cells

Recombinant Human Dual specificity protein kinase CLK3(CLK3) - CSB-YP005560HU CSB-EP005560HU CSB-BP005560HU CSB-MP005560HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human CLK3 Protein (GST tag) - PKSH031459 from Elabscience Category Protein Source Baculoviru Species Human

CLK3 Protein - NBP1-91794PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

CLK3-Antibody-N-term-Blocking-Peptide - BP7531a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CLK3 Peptide, Human - M34GP03294H from Creative Peptides Category Peptide Source Synthetic. Species Human

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