CLK3

Gene Symbol CLK3
Entrez Gene 1198
Alt Symbol PHCLK3, PHCLK3/152
Species Human
Gene Type protein-coding
Description CDC-like kinase 3
Other Description dual specificity protein kinase CLK3
Swissprots Q9BUJ7 D3DW59 Q53Y48 Q9BRS3 P49761
Accessions EAW99320 EAW99321 EAW99322 EAW99323 EAW99324 EAW99325 P49761 AB209535 BAD92772 AK026511 AK091692 BAG52400 AK095335 AK096115 BAG53214 AK097982 BAG53559 AK122860 BAG53765 AK225680 AK291983 BAF84672 AK293769 BAG57185 AK301689 BAG63161 AL833165 BC002555 AAH02555 BC006103 AAH06103 BC009857 BC019881 AAH19881 BI459843 BM678884 BQ183959 BT006993 AAP35639 CR933693 JF432199 ADZ15416 L29217 AAA61484 L29220 AAA61483 XM_005254151 XP_005254208 XM_005254153 XP_005254210 XM_006720384 XP_006720447 XM_011521205 XP_011519507 XM_011521206 XP_011519508 XM_011521207 XP_011519509 XM_011521208 XP_011519510 XM_011521209 XP_011519511 XM_011521210 XP_011519512 XR_931746 NM_001130028 NP_001123500 NM_003992 NP_003983 NM_001292
Function Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. {ECO:0000269|PubMed:19168442, ECO:0000269|PubMed:9637771}.
Subcellular Location Isoform 1: Nucleus. Cytoplasm {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}.
Tissue Specificity Endothelial cells. {ECO:0000269|PubMed:19168442}.

CLK3 Antibody - 3256 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from Jurkat, HT29 and PC12 cell lines using CLK3 Antibody.

CLK3 (D-10) - sc-365225 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CLK3 (D-10): sc-365225. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing nuclear and cytoplasmic staining of Leydig cells.

CLK3 (D-15) - sc-79904 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CLK3 (D-15): sc-79904. Western blot analysis of CLK3 expression in non-transfected 293T: sc-117752 (A), human CLK3 transfected 293T: sc-158386 (B) and Jurkat (C) whole cell lysates.

CLK3 (E-14) - sc-79905 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CLK3 (E-14): sc-79905. Western blot analysis of CLK3 expression in non-transfected: sc-117752 (A) and human CLK3 transfected: sc-158386 (B) 293T whole cell lysates.

CLK3 (H-249) - sc-292980 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

CLK3 (S-19) - sc-79906 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CLK3 (S-19): sc-79906. Western blot analysis of CLK3 expression in non-transfected: sc-117752 (A) and human CLK3 transfected: sc-158386 (B) 293T whole cell lysates.

CLK3 (Y-13) - sc-79907 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CLK3 (4F12) - sc-134301 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CLK3 (4F12): sc-134301. Western blot analysis of CLK3 expression in non-transfected 293T: sc-117752 (A), human CLK3 transfected 293T: sc-158385 (B) and Jurkat (C) whole cell lysates.

Anti-CLK3 antibody - ab88135 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-CLK3 antibody (ab88135) at 5 µg/ml + recombinant protein (immunogen) at 0.2 µg/mlSecondaryGoat anti-mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

Anti-CLK3 antibody - ab54683 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
CLK3 antibody (ab54683) used in immunohistochemistry at 5ug/ml on formalin fixed and paraffin embedded human testis.

Anti-CLK3 antibody - ab183768 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of HeLa cells (fixed in 4% paraformaldehyde at room temperature for 15 mins) labeling CLK3 with ab183768 at 1/500 dilution (green). Blue: Hoechst 33342 staining.

Anti-CLK3 Antibody (His51) - LS-C35949 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK3 Antibody (aa19-48, APC) - LS-C255053 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK3 Antibody (aa19-48, AP) - LS-C255054 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK3 Antibody (aa19-48, Azide-free, HRP) - LS-C255057 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK3 Antibody (aa19-48, Biotin) - LS-C255055 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK3 Antibody (aa19-48, PE) - LS-C255059 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK3 Antibody (aa19-48, FITC) - LS-C255056 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK3 Antibody (aa19-48) - LS-C329390 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CLK3 Antibody (N-Terminus) - LS-C345493 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of CLK3 Antibody with human HeLa Whole Cell lysate.

Anti-CLK3 Antibody (aa19-48) - LS-C164348 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Mouse Clk3 Antibody western blot of mouse testis tissue lysates (35 ug/lane). The Clk3 antibody detected the Clk3 protein (arrow).

Anti-CLK3 Antibody (clone 1H2) - LS-C133121 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1H2
Immunoperoxidase of monoclonal antibody to CLK3 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 0.2 ug/ml]

Anti-CLK3 Antibody (clone 5B2) - LS-C133122 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5B2
Immunoperoxidase of monoclonal antibody to CLK3 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1.5 ug/ml]

Anti-CLK3 Antibody (clone 7D6) - LS-C133124 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7D6
Immunoperoxidase of monoclonal antibody to CLK3 on formalin-fixed paraffin-embedded human prostate. [antibody concentration 3 ug/ml]

Anti-CLK3 Antibody (clone 1F10) - LS-C133123 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F10
Immunoperoxidase of monoclonal antibody to CLK3 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 0.5 ug/ml]
Search more