MLYCD

Gene Symbol	MLYCD
Entrez Gene	23417
Alt Symbol	MCD
Species	Human
Gene Type	protein-coding
Description	malonyl-CoA decarboxylase
Other Description	malonyl coenzyme A decarboxylase|malonyl-CoA decarboxylase, mitochondrial
Swissprots	Q9UNU5 Q9Y3F2 O95822
Accessions	EAW95513 O95822 AF090834 AAD48994 AF097832 AAD16177 AF153679 AAD34631 AK094095 BC000286 AAH00286 BC052592 AAH52592 NM_012213 NP_036345
Function	Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids. Plays a role in the metabolic balance between glucose and lipid oxidation in muscle independent of alterations in insulin signaling. May play a role in controlling the extent of ischemic injury by promoting glucose oxidation. {ECO:0000269|PubMed:10455107, ECO:0000269|PubMed:15003260, ECO:0000269|PubMed:18314420, ECO:0000269|PubMed:23482565}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:10417274}. Mitochondrion matrix {ECO:0000269|PubMed:10417274}. Peroxisome {ECO:0000269|PubMed:10417274}. Peroxisome matrix {ECO:0000250}. Note=Enzymatically active in all three subcellular compartments. {ECO:0000250}.
Tissue Specificity	Expressed in fibroblasts and hepatoblastoma cells (at protein level). Expressed strongly in heart, liver, skeletal muscle, kidney and pancreas. Expressed in myotubes. Expressed weakly in brain, placenta, spleen, thymus, testis, ovary and small intestine. {ECO:0000269|PubMed:10455107, ECO:0000269|PubMed:18314420}.
Top Pathways	Peroxisome, AMPK signaling pathway, beta-Alanine metabolism, Propanoate metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

malonyl coenzyme A, ELISA Kit - MBS2602799 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

malonyl coenzyme A, ELISA Kit - MBS705079 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.156 ng/ml Range 0.625 ng/ml-40 ng/ml

malonyl coenzyme A, ELISA Kit - MBS701511 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.625 ng/ml Range 1.25 ng/ml-20 ng/ml

Malonyl Coenzyme A Decarboxylase (MLYCD), ELISA Kit - MBS2601474 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Malonyl Coenzyme A Decarboxylase (MLYCD), ELISA Kit - MBS2601228 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Malonyl Coenzyme A Decarboxylase (MLYCD), ELISA Kit - MBS2602378 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Malonyl Coenzyme A Decarboxylase (MLYCD), ELISA Kit - MBS269964 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.05 ng/ml. Range 10 ng/ml-0.156 ng/ml

Malonyl Coenzyme A Decarboxylase (MLYCD), ELISA Kit - MBS2601869 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Malonyl Coenzyme A Decarboxylase (MLYCD), ELISA Kit - MBS2601385 from MyBioSource Category ELISA Kit Prices $275.00, $420.00, $1,615.00, $2,880.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Up to 0.06 ng/ml. Range 20 ng/ml-0.312 ng/ml

Malonyl Coenzyme A Decarboxylase (MLYCD), ELISA Kit - MBS2601663 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.05 ng/ml. Range 10 ng/ml-0.156 ng/ml

Malonyl Coenzyme A Decarboxylase (MLYCD), ELISA Kit - MBS2601690 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

malonyl-CoA decarboxylase, ELISA Kit - MBS908311 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human MLYCD is typically less than 7.81 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 31.25 pg/ml -2000 pg/ml.

Malonyl-CoA Decarboxylase, Mitochondrial, ELISA Kit - MBS102463 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Malonyl-CoA Decarboxylase, Mitochondrial, ELISA Kit - MBS087897 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Malonyl-CoA Decarboxylase, Mitochondrial, ELISA Kit - MBS089272 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Malonyl-CoA Decarboxylase, Mitochondrial, ELISA Kit - MBS079067 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Malonyl-CoA Decarboxylase, Mitochondrial, ELISA Kit - MBS086498 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Malonyl-CoA Decarboxylase, Mitochondrial, ELISA Kit - MBS092138 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Malonyl-CoA decarboxylase, mitochondrial (MLYCD), ELISA Kit - MBS7219277 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Malonyl-CoA decarboxylase, mitochondrial(MLYCD) ELISA kit - CSB-EL014646HU from Cusabio Category ELISA Kit Sensitivity 7.81 pg/ml Range 31.25 pg/ml-2000 pg/ml

Malonyl-CoA Decarboxylase, Mitochondrial, ELISA Kit - MBS088839 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Malonyl-CoA decarboxylase, mitochondrial (MLYCD) ELISA Kit - EKC34529 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 7.81 pg/ml Range 31.25 pg/ml-2000 pg/ml

Human MLYCD ELISA Kit - E023554 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human MLYCD is typically less than 7.81 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the me

MLYCD ELISA Kit (Human) (OKCA01346) - OKCA01346 from Aviva Systems Biology Category ELISA Kit Prices $600.00 Sizes 96 wells Sensitivity 7.81 pg/mL Range 31.25 - 2,000 pg/mL

Malonyl Coenzyme A Decarboxylase (MLYCD), ELISA Kit - MBS2609988 from MyBioSource Category ELISA Kit Prices $300.00, $475.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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