MLYCD

Gene Symbol	MLYCD
Entrez Gene	23417
Alt Symbol	MCD
Species	Human
Gene Type	protein-coding
Description	malonyl-CoA decarboxylase
Other Description	malonyl coenzyme A decarboxylase|malonyl-CoA decarboxylase, mitochondrial
Swissprots	Q9UNU5 Q9Y3F2 O95822
Accessions	EAW95513 O95822 AF090834 AAD48994 AF097832 AAD16177 AF153679 AAD34631 AK094095 BC000286 AAH00286 BC052592 AAH52592 NM_012213 NP_036345
Function	Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids. Plays a role in the metabolic balance between glucose and lipid oxidation in muscle independent of alterations in insulin signaling. May play a role in controlling the extent of ischemic injury by promoting glucose oxidation. {ECO:0000269|PubMed:10455107, ECO:0000269|PubMed:15003260, ECO:0000269|PubMed:18314420, ECO:0000269|PubMed:23482565}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:10417274}. Mitochondrion matrix {ECO:0000269|PubMed:10417274}. Peroxisome {ECO:0000269|PubMed:10417274}. Peroxisome matrix {ECO:0000250}. Note=Enzymatically active in all three subcellular compartments. {ECO:0000250}.
Tissue Specificity	Expressed in fibroblasts and hepatoblastoma cells (at protein level). Expressed strongly in heart, liver, skeletal muscle, kidney and pancreas. Expressed in myotubes. Expressed weakly in brain, placenta, spleen, thymus, testis, ovary and small intestine. {ECO:0000269|PubMed:10455107, ECO:0000269|PubMed:18314420}.
Top Pathways	Peroxisome, AMPK signaling pathway, beta-Alanine metabolism, Propanoate metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MLYCD full length protein - ab161633 from Abcam Category Protein Source Wheat germ Species Human

MLYCD Recombinant Protein - H00023417-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human MLYCD Protein - NBP1-98961 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E.coli Species Human

MLYCD-Antibody-N-term-Blocking-Peptide - BP19619a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MLYCD - H00023417-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MLYCD - H00023417-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MLYCD fusion protein - Ag7334 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

MLYCD fusion protein - Ag18825 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human MLYCD, GST-tagged - MLYCD-913H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Malonyl-CoA decarboxylase, mitochondrial(MLYCD) ,partial - CSB-YP014646HU CSB-EP014646HU CSB-BP014646HU CSB-MP014646HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Malonyl Coenzyme A Decarboxylase (MLYCD) - RPB664Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

MLYCD - TP308587 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

MLYCD Recombinant Protein Antigen - NBP1-83247PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MLYCD Peptide, Human - M34GP09580H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human O95822 protein - orb8225 from Biorbyt Category Protein Prices $255.00, $442.00, $510.00, $825.00, $1,369.00, $2,185.00 Sizes 10 μg, 50 μg, 100 μg, 200 μg, 500 μg, 1 mg Species Human

Recombinant Human Malonyl-CoA decarboxylase, mitochondrial(MLYCD) - RPC20544 from Biomatik Category Protein Prices $132.00, $297.00, $466.00, $728.00, $1,159.00, $1,753.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Recombinant Malonyl Coenzyme A Decarboxylase (MLYCD) - RPU51162 from Biomatik Category Protein Prices $167.00, $342.00, $523.00, $653.60 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

MLYCD Recombinant Protein (OPCD00677) - OPCD00677 from Aviva Systems Biology Category Protein Source E.coli Species Human

Malonyl Coenzyme A Decarboxylase, Recombinant Protein - MBS2033298 from MyBioSource Category Protein Prices $170.00, $345.00, $535.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Malonyl-CoA decarboxylase, mitochondrial (MLYCD), partial, Recombinant Protein - MBS1208208 from MyBioSource Category Protein Prices $1,235.00, $1,235.00, $1,465.00, $1,465.00, $1,985.00, $1,985.00, $2,445.00, $2,445.00, $2,445.00, $3,925.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

MLYCD Recombinant Protein (Human) (OPCA05139) - OPCA05139 from Aviva Systems Biology Category Protein Species Human

Search more