Gene Symbol | SIGLEC8 |
---|---|
Entrez Gene | 27181 |
Alt Symbol | SAF2, SIGLEC-8, SIGLEC8L |
Species | Human |
Gene Type | protein-coding |
Description | sialic acid binding Ig-like lectin 8 |
Other Description | CDw329|SAF-2|sialic acid-binding Ig-like lectin 8|sialoadhesin family member 2 |
Swissprots | Q9NYZ4 Q7Z728 |
Accessions | AAG00573 EAW72018 EAW72019 EAW72020 Q9NYZ4 AF195092 AAF27622 AF223403 AAF34702 AF310234 AAK55140 AK290149 BAF82838 AK290412 BAF83101 AK295589 BAG58481 BC053319 AAH53319 DA388103 XM_011526734 XP_011525036 XM_011526735 XP_011525037 NM_014442 NP_055257 |
Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed specifically on eosinophils. |
Human SIGLEC8 cDNA clone(NM_014442.2) - CDFH017570 from Creative Biomart
|
||||||
human SIGLEC8 ORF clone - CDCH080240 from Creative Biomart
|
||||||
human SIGLEC8 ORF clone - CDCH080241 from Creative Biomart
|
||||||
human SIGLEC8 ORF clone - CDCH080242 from Creative Biomart
|
||||||
human SIGLEC8 ORF clone - CDCH080243 from Creative Biomart
|
||||||
Human SIGLEC8 ORF clone(NM_014442.2) - CDCH400450 from Creative Biomart
|
||||||
Human SIGLEC8 ORF Clone(NM_014442.2) - CDCL175477 from Creative Biomart
|
||||||
Human SIGLEC8 ORF Clone(NM_014442.2) - CDCR297421 from Creative Biomart
|
||||||
Human SIGLEC8 ORF Clone(NM_014442.2) - CDCR297422 from Creative Biomart
|
||||||
Human SIGLEC8 ORF Clone(NM_014442.2) - CDCR297423 from Creative Biomart
|
||||||
Human Siglec-8 (NP_055257) VersaClone cDNA - RDC1496 from R&D Systems
|
||||||
human SIGLEC8 ORF clone (NM_014442.2) - CDCH080240 from Creative biogene
|
||||||
Human SIGLEC8 cDNA Clone(NM_014442.2) - CDFH017570 from Creative biogene
|
||||||