SIGLEC8

Gene Symbol	SIGLEC8
Entrez Gene	27181
Alt Symbol	SAF2, SIGLEC-8, SIGLEC8L
Species	Human
Gene Type	protein-coding
Description	sialic acid binding Ig-like lectin 8
Other Description	CDw329|SAF-2|sialic acid-binding Ig-like lectin 8|sialoadhesin family member 2
Swissprots	Q9NYZ4 Q7Z728
Accessions	AAG00573 EAW72018 EAW72019 EAW72020 Q9NYZ4 AF195092 AAF27622 AF223403 AAF34702 AF310234 AAK55140 AK290149 BAF82838 AK290412 BAF83101 AK295589 BAG58481 BC053319 AAH53319 DA388103 XM_011526734 XP_011525036 XM_011526735 XP_011525037 NM_014442 NP_055257
Function	Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed specifically on eosinophils.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SIGLEC8 protein fragment - ab162108 from Abcam Category Protein Source Wheat germ Species Human

SIGLEC8 Antibody Blocking Peptide - LS-E3390 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SIGLEC8 Antibody Blocking Peptide - LS-E4044 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SIGLEC8 Antibody Blocking Peptide - LS-E26917 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Siglec-8 Protein - H00027181-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Siglec-8 Protein - H00027181-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

Siglec-8 Peptide - P0601 from Novus Biologicals Category Peptide Species Human

SIGLEC8-Antibody-N-term-Blocking-Peptide - BP14564a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SIGLEC8-Antibody-C-term-Blocking-Peptide - BP1626b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SIGLEC8 blocking peptide - GTX88527-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

SIGLEC8 Immunizing peptide - orb16931 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

SIGLEC8 Peptide - AC21-1748-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CD329 / SIGLEC8 - H00027181-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD329 / SIGLEC8 - H00027181-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD329 / SIGLEC8 - H00027181-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Sialic Acid Binding Ig Like Lectin 8 (SIGLEC8), Human - 20-8015 from ARP American Research Products Category Protein Prices $629.00 Sizes 50 µg Source E.coli Species Human

SIGLEC-8 Peptide - 46-758P from ProSci Category Peptide Species Human

SIGLEC8 fusion protein - ag10043 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human SIGLEC8, His-tagged - SIGLEC8-2670H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Sialic Acid Binding Ig Like Lectin 8 (SIGLEC8) - RPB790Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Sialic Acid Binding Ig Like Lectin 8 (SIGLEC8) - RPB790Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Sialic acid-binding Ig-like lectin 8(SIGLEC8) - CSB-YP878931HU CSB-EP878931HU CSB-BP878931HU CSB-MP878931HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CD329 / SIGLEC8 - TP308582 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SIGLEC8, Peptide - MBS426267 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

Recombinant Human Siglec-8 Fc Chimera Protein, CF - 9045-SL from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Human Siglec-8 (Met17-Ala363) Accession # AAH53319 IEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus Species Human

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