SIGLEC8

Gene Symbol SIGLEC8
Entrez Gene 27181
Alt Symbol SAF2, SIGLEC-8, SIGLEC8L
Species Human
Gene Type protein-coding
Description sialic acid binding Ig-like lectin 8
Other Description CDw329|SAF-2|sialic acid-binding Ig-like lectin 8|sialoadhesin family member 2
Swissprots Q9NYZ4 Q7Z728
Accessions AAG00573 EAW72018 EAW72019 EAW72020 Q9NYZ4 AF195092 AAF27622 AF223403 AAF34702 AF310234 AAK55140 AK290149 BAF82838 AK290412 BAF83101 AK295589 BAG58481 BC053319 AAH53319 DA388103 XM_011526734 XP_011525036 XM_011526735 XP_011525037 NM_014442 NP_055257
Function Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed specifically on eosinophils.

Siglec-8 CRISPR/Cas9 KO Plasmid (h) - sc-409894 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-8 HDR Plasmid (h) - sc-409894-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-8 Double Nickase Plasmid (h) - sc-409894-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-8 Double Nickase Plasmid (h2) - sc-409894-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-8 CRISPR Activation Plasmid (h) - sc-409894-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-8 CRISPR Activation Plasmid (h2) - sc-409894-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-8 Lentiviral Activation Particles (h) - sc-409894-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-8 Lentiviral Activation Particles (h2) - sc-409894-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Siglec-8 siRNA (h) - sc-61551 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Siglec-8 shRNA Plasmid (h) - sc-61551-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Siglec-8 shRNA (h) Lentiviral Particles - sc-61551-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Siglec-8 RNAi - H00027181-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU074421 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN19336 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19336 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09460 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09460

SIGLEC8 siRNA (Human) - CRH9013 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SIGLEC8 - MBS8200168 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SIGLEC8 (NM_014442.2) - SHH407484 from Creative biogene

Category siRNA
Species Reactivities Human

Human SIGLEC8 siRNA - orb269515 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SIGLEC8 shRNA Plasmid (Human) - CHH9013 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SIGLEC8 miRNA 3'UTR clone - MiUTR1H-09397 from Creative biogene

Species Reactivities Human
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