APITD1

Gene Symbol APITD1
Entrez Gene 378708
Alt Symbol CENP-S, CENPS, FAAP16, MHF1
Species Human
Gene Type protein-coding
Description apoptosis-inducing, TAF9-like domain 1
Other Description FANCM-interacting histone fold protein 1|Fanconi anemia-associated polypeptide of 16 kDa|apoptosis-inducing TAF9-like domain-containing protein 1|centromere protein S
Swissprots Q8NFG5 Q8N2Z9 Q8NFE5
Accessions CAI19199 EAW71654 Q8N2Z9 BC029430 AAH29430 BE858209 BG213105 BG546364 BM905996 BU902753 CA311915 HQ447791 ADQ32275 NM_199294 NP_954988 NR_036462
Function DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance. Required for optimal chromatin association of the FA core complex. Required for efficient damage-induced monoubiquitination and focus formation of FANCD2. Stabilizes FAAD24, FANCM and STRA13/CENPX in the FA core complex. Plays a role in DNA interstrand cross-linking (ICL) repair and in recovery of replication forks stalled by topoisomerase I-DNA cleavage intermediates induced by camptothecin. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. Component of the APITD1/CENPS complex that is essential for the stable assembly of the outer kinetochore. Plays an important role in mitotic progression and chromosome segregation. Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segr
Subcellular Location Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Constitutively localizes to centromeres throughout the cell cycle, and to kinetochores during mitosis. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:15328517}.
Top Pathways Fanconi anemia pathway

Centromere protein S (APITD1), Human, ELISA Kit - E01C0940 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 0.1ng/ml
Range 1.0-25ng/ml

Centromere protein S (APITD1), Human, ELISA Kit - E01C1191 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Centromere protein S (APITD1), ELISA Kit - MBS7213586 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Centromere protein S (APITD1), ELISA Kit - MBS7229720 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Centromere protein S (APITD1), ELISA Kit - MBS7246872 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Centromere protein S (APITD1), ELISA Kit - MBS7203352 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Centromere protein S (APITD1), ELISA Kit - MBS7242046 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Centromere protein S (APITD1), ELISA Kit - MBS7233654 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Centromere protein S (APITD1), ELISA Kit - MBS7200422 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Centromere protein S (APITD1), ELISA Kit - MBS7253169 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Centromere protein S (APITD1), ELISA Kit - MBS7222232 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Centromere protein S (APITD1), ELISA Kit - MBS7210723 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Centromere protein S (APITD1), ELISA Kit - MBS7209979 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Centromere protein S (APITD1), ELISA Kit - MBS7250941 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human APITD1 ELISA Kit - E007791 from Biobool

Category ELISA Kit

anti-MHF1 antibody - ARG57366 from Arigo Biolaboratories

Category ELISA Kit
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