TRPC6

Gene Symbol	TRPC6
Entrez Gene	7225
Alt Symbol	FSGS2, TRP6
Species	Human
Gene Type	protein-coding
Description	transient receptor potential cation channel, subfamily C, member 6
Other Description	TRP-6|focal segmental glomerulosclerosis 2|short transient receptor potential channel 6|transient receptor protein 6
Swissprots	Q9NQA8 Q9Y210 Q9HCW3 Q9NQA9 Q52M59
Accessions	EAW67003 EAW67004 EAW67005 Q9Y210 AF080394 AAC63289 AF086426 AJ006276 CAA06943 AJ007018 CAC06090 AJ271066 CAC01684 AJ271067 CAC01685 AJ271068 CAC01686 AK001960 AK027769 BAG51375 BC093658 AAH93658 BC093660 AAH93660 XM_006718898 XP_006718961 XM_011542968 XP_011541270 XM_011542969 XP_011541271 NM_004621 NP_004612
Function	Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.
Subcellular Location	Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity	Expressed primarily in placenta, lung, spleen, ovary and small intestine. Expressed in podocytes and is a component of the glomerular slit diaphragm. {ECO:0000269|PubMed:15924139}.
Top Pathways	cGMP-PKG signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TRPC6 ELISA Kit (Sandwich ELISA) - LS-F9417 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.312 ng/ml Range 0.312-20 ng/ml

Transient Receptor Potential Cation Channel Subfamily C, Member 6 (TRPC6), Human, ELISA Kit - SEF846Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.129ng/mL Range 0.312-20ng/mL

transient receptor potential cation channel, subfamily C, member 6, ELISA Kit - MBS9330948 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.25ng/ml-8ng/ml.

ELISA Kit for Transient Receptor Potential Cation Channel Subfamily C, Member 6 (TRPC6) - SEF846Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.129ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Transient Receptor Potential Cation Channel Subfamily C, Member 6 (TRPC6) - SEF846Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.129ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human TRPC6 ELISA Kit - abx153394 from Abbexa Category ELISA Kit Sensitivity 0.129 ng/ml Range 0.313 ng/ml - 20 ng/ml

Transient Receptor Potential Cation Channel Subfamily C, Member 6 (TRPC6), Human, ELISA Kit - DL-TRPC6-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human TRPC6 ELISA Kit - abx573121 from Abbexa Category ELISA Kit Sensitivity 0.129 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human TRPC6 ELISA Kit - E039016 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human TRPC6 is typically less than 0.129ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by add

TRPC6 ELISA Kit (Human) (OKCD00985) - OKCD00985 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.129 ng/mL Range 0.312-20 ng/mL

anti-TRPC6 antibody - ARG51301 from Arigo Biolaboratories Category ELISA Kit

anti-TRPC6 antibody - ARG64683 from Arigo Biolaboratories Category ELISA Kit

anti-TRPC6 antibody - ARG63815 from Arigo Biolaboratories Category ELISA Kit

Human Short transient receptor potential channel 6 (TRPC6) ELISA Kit - AE13239HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.113 ng/mL Range 0.312-20 ng/mL

Short Transient Receptor Potential Channel 6 (TRPC6), ELISA Kit - MBS9389186 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Short Transient Receptor Potential Channel 6 (TRPC6), ELISA Kit - MBS9389194 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Short Transient Receptor Potential Channel 6 (TRPC6), ELISA Kit - MBS9389179 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Short Transient Receptor Potential Channel 6 (TRPC6), ELISA Kit - MBS9389182 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Short Transient Receptor Potential Channel 6 (TRPC6), ELISA Kit - MBS9389180 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Short Transient Receptor Potential Channel 6 (TRPC6), ELISA Kit - MBS9389181 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Short Transient Receptor Potential Channel 6 (TRPC6), ELISA Kit - MBS9389185 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Short Transient Receptor Potential Channel 6 (TRPC6), ELISA Kit - MBS9389190 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Short Transient Receptor Potential Channel 6 (TRPC6), ELISA Kit - MBS9389183 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Short Transient Receptor Potential Channel 6 (TRPC6), ELISA Kit - MBS9389187 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Short Transient Receptor Potential Channel 6 (TRPC6), ELISA Kit - MBS9389189 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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