SF3B3

Gene Symbol SF3B3
Entrez Gene 23450
Alt Symbol RSE1, SAP130, SF3b130, STAF130
Species Human
Gene Type protein-coding
Description splicing factor 3b, subunit 3, 130kDa
Other Description SAP 130|pre-mRNA splicing factor SF3b, 130 kDa subunit|pre-mRNA-splicing factor SF3b 130 kDa subunit|spliceosome-associated protein 130|splicing factor 3B subunit 3|splicing factor 3b, subunit 3, 130kD
Swissprots Q9BPY2 Q96GC0 Q6NTI8 Q15393 Q9UJ29 Q9UFX7
Accessions EAW51803 EAW51804 EAW51805 Q15393 AJ001443 CAB56791 AK001297 BAG50889 AK074933 BAG52033 AK291768 BAF84457 AL110251 CAB53699 AW449427 BC000463 AAH00463 BC003146 AAH03146 BC009780 AAH09780 BC068974 AAH68974 BI465052 CB241776 D13642 BAA02805 D87686 BAA32662 JF432652 ADZ15869 NM_012426 NP_036558
Function Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
Subcellular Location Nucleus {ECO:0000269|PubMed:11564863}.
Top Pathways Spliceosome

Mouse SF3B130 / SF3B3 ELISA Kit (Sandwich ELISA) - LS-F8483 from LifeSpan Bioscience

Category ELISA Kit
Prices $810.00
Sizes 1 plate
Sensitivity 0.156 ng/ml
Range 0.156-10 ng/ml

Splicing Factor 3B Subunit 3, ELISA Kit - MBS075781 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Splicing Factor 3B Subunit 3, ELISA Kit - MBS083539 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1 ng/ml.
Range 0.25 ng/ml - 8 ng/ml.

Splicing Factor 3B Subunit 3, ELISA Kit - MBS049769 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Splicing Factor 3B Subunit 3, ELISA Kit - MBS066411 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Splicing Factor 3B Subunit 3, ELISA Kit - MBS081857 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Splicing Factor 3B Subunit 3, ELISA Kit - MBS100033 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Splicing Factor 3B Subunit 3, ELISA Kit - MBS101832 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Splicing Factor 3B Subunit 3 (SF3B3), ELISA Kit - MBS2022310 from MyBioSource

Category ELISA Kit
Prices $420.00, $625.00, $855.00, $3,510.00, $6,365.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of mouse SF3B3 is typically less than 0.056ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration.
Range 0.156-10ng/mL

ELISA Kit for Splicing Factor 3B Subunit 3 (SF3B3) - SEM216Mu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.056ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

SimpleChIP ® Human SF3B3 Exon 1 Primers - 62858 from Cell Signaling Technology

Category ChIP Kit
Prices $102.00
Sizes 500 µl (250 PCR reactions)
SimpleChIP ® Human SF3B3 Exon 1 Primers were tested on DNA isolated from cross-linked cells using the SimpleChIP ® Enzymatic Chromatin IP Kit (Magnetic Beads) #9003. Real-time PCR was performed in duplicate on a serial dilution of 2% total input DNA (20 ng, 4 ng, 0.8 ng, and 0.16 ng) using a real-time PCR detection system and SYBR ® Green reaction mix. The PCR amplification efficiency (E) and correlation coefficient (R 2 ) were calculated based on the corresponding threshold cycle (C T ) of each dilution sample during 40 cycles of real-time PCR (95°C denaturation for 15 sec, 65°C anneal/extension for 60 sec).

Human SF3B3 ELISA Kit - E097651 from Biobool

Category ELISA Kit

Splicing Factor 3B Subunit 3 (SF3B3), ELISA Kit - MBS9376676 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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