SF3B3

Gene Symbol SF3B3
Entrez Gene 23450
Alt Symbol RSE1, SAP130, SF3b130, STAF130
Species Human
Gene Type protein-coding
Description splicing factor 3b, subunit 3, 130kDa
Other Description SAP 130|pre-mRNA splicing factor SF3b, 130 kDa subunit|pre-mRNA-splicing factor SF3b 130 kDa subunit|spliceosome-associated protein 130|splicing factor 3B subunit 3|splicing factor 3b, subunit 3, 130kD
Swissprots Q9BPY2 Q96GC0 Q6NTI8 Q15393 Q9UJ29 Q9UFX7
Accessions EAW51803 EAW51804 EAW51805 Q15393 AJ001443 CAB56791 AK001297 BAG50889 AK074933 BAG52033 AK291768 BAF84457 AL110251 CAB53699 AW449427 BC000463 AAH00463 BC003146 AAH03146 BC009780 AAH09780 BC068974 AAH68974 BI465052 CB241776 D13642 BAA02805 D87686 BAA32662 JF432652 ADZ15869 NM_012426 NP_036558
Function Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
Subcellular Location Nucleus {ECO:0000269|PubMed:11564863}.
Top Pathways Spliceosome

SF3B3 CRISPR/Cas9 KO Plasmid (h) - sc-408209 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SF3B3 HDR Plasmid (h) - sc-408209-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SF3B3 Double Nickase Plasmid (h) - sc-408209-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SF3B3 Double Nickase Plasmid (h2) - sc-408209-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SF3B3 CRISPR Activation Plasmid (h) - sc-408209-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SF3B3 CRISPR Activation Plasmid (h2) - sc-408209-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SF3B3 Lentiviral Activation Particles (h) - sc-408209-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SF3B3 Lentiviral Activation Particles (h2) - sc-408209-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SF3B3 siRNA (h) - sc-38314 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SF3B3 shRNA Plasmid (h) - sc-38314-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SF3B3 shRNA (h) Lentiviral Particles - sc-38314-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SAP130 RNAi - H00023450-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU079281 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19188 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19188 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR13001 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr13001

SF3B3 siRNA (Human) - CRH8277 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SF3B3 - MBS8237456 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SF3B3 (NM_012426.4) - SHH405836 from Creative biogene

Category siRNA
Species Reactivities Human

SF3B3 shRNA Plasmid (Human) - CHH8277 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SF3B3 miRNA 3'UTR clone - MiUTR4H-TG07980 from Creative biogene

Species Reactivities Human
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