SF3B3

Gene Symbol	SF3B3
Entrez Gene	23450
Alt Symbol	RSE1, SAP130, SF3b130, STAF130
Species	Human
Gene Type	protein-coding
Description	splicing factor 3b, subunit 3, 130kDa
Other Description	SAP 130|pre-mRNA splicing factor SF3b, 130 kDa subunit|pre-mRNA-splicing factor SF3b 130 kDa subunit|spliceosome-associated protein 130|splicing factor 3B subunit 3|splicing factor 3b, subunit 3, 130kD
Swissprots	Q9BPY2 Q96GC0 Q6NTI8 Q15393 Q9UJ29 Q9UFX7
Accessions	EAW51803 EAW51804 EAW51805 Q15393 AJ001443 CAB56791 AK001297 BAG50889 AK074933 BAG52033 AK291768 BAF84457 AL110251 CAB53699 AW449427 BC000463 AAH00463 BC003146 AAH03146 BC009780 AAH09780 BC068974 AAH68974 BI465052 CB241776 D13642 BAA02805 D87686 BAA32662 JF432652 ADZ15869 NM_012426 NP_036558
Function	Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
Subcellular Location	Nucleus {ECO:0000269|PubMed:11564863}.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SF3B3 protein fragment - ab153230 from Abcam Category Protein Source Wheat germ Species Human

SF3B130 / SF3B3 Antibody Blocking Peptide - LS-E1873 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SF3B130 / SF3B3 Antibody Blocking Peptide - LS-E14919 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SF3B130 / SF3B3 Antibody Blocking Peptide - LS-E14920 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SF3B130 / SF3B3 Antibody Blocking Peptide - LS-E25398 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SAP130 Protein - H00023450-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SF3B3-Antibody-C-term-Blocking-peptide - BP12703b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SAP130 blocking peptide - GTX89893-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

SF3B3 Blocking Peptide - 33R-2457 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SF3B3 Blocking Peptide - 33R-9341 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SF3B3 Peptide - AC21-0226-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SF3B3 / SAP130 - H00023450-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SF3B3 / SAP130 - H00023450-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SF3B3 Peptide - 46-363P from ProSci Category Peptide Species Human

SF3B3 fusion protein - Ag6315 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

SF3B3 fusion protein - Ag5980 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SF3B3, His-tagged - SF3B3-2613H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Splicing Factor 3B Subunit 3 (SF3B3) - RPM216Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Splicing Factor 3B Subunit 3 (SF3B3) - RPM216Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

SAP130 Blocking Peptide - CBP2574 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Zebrafish

SF3B3 Peptide - BS5926P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Splicing factor 3B subunit 3(SF3B3) ,partial - CSB-YP614890HU CSB-EP614890HU CSB-BP614890HU CSB-MP614890HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SF3B3 Protein - abx164524 from Abbexa Category Protein Species Human, Rat

SF3B3 / SAP130 - TP309509 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SAP130/SF3B3, Peptide - MBS425440 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine

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