F2

Gene Symbol	F2
Entrez Gene	2147
Alt Symbol	PT, RPRGL2, THPH1
Species	Human
Gene Type	protein-coding
Description	coagulation factor II (thrombin)
Other Description	prepro-coagulation factor II|prothrombin|prothrombin B-chain|serine protease
Swissprots	Q53H06 B2R7F7 P00734 Q7Z7P3 Q4QZ40 Q53H04 Q9UCA1 B4E1A7 Q69EZ7
Accessions	AAB24476 AAC63054 AAL77436 AAM11680 CAD80258 CAL24231 EAW67977 EAW67978 EAW67979 P00734 AJ972449 CAJ01369 AK222775 BAD96495 AK222777 BAD96497 AK293326 BAG56844 AK303747 BAG64719 AK312965 BAG35804 AY344793 AAR08142 AY344794 AAR08143 BC051332 AAH51332 CB156997 DB183734 EU832664 ACE87755 EU832742 ACE87074 M33031 AAA60220 V00595 CAA23842 XR_428840 NM_000506 NP_000497
Function	Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. {ECO:0000269|PubMed:2856554}.
Subcellular Location	Secreted, extracellular space.
Tissue Specificity	Expressed by the liver and secreted in plasma.
Top Pathways	Complement and coagulation cascades, Regulation of actin cytoskeleton, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Prothrombin (Factor II) Human ELISA - ab108889 from Abcam Prices $489.00 Sizes 1 x 96 tests Sensitivity = 0.03 µg/ml Range 0.031 µg/ml - 32 µg/ml

Thrombin Activity Assay Kit (Fluorometric) - ab197006 from Abcam Category Cellular Assay Prices $560.00 Sizes 100 tests Sensitivity 1 ng

Thrombin Inhibitor Screening Assay Kit (Fluorometric) - ab197007 from Abcam Category Cellular Assay Prices $670.00 Sizes 100 tests

Human F2 / Prothrombin / Thrombin ELISA Kit (Sandwich ELISA) - LS-F4268 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 4.69 ng/ml Range 4.69-300 ng/ml

Mouse/Human/Rat F2 / Prothrombin / Thrombin ELISA Kit (Cell-Based ELISA) - LS-F3047 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 4.69-300 ng/ml

Rat F2 / Prothrombin / Thrombin ELISA Kit (Sandwich ELISA) - LS-F4125 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 1.45 ng/ml Range 4.69-300 ng/ml

Mouse F2 / Prothrombin / Thrombin ELISA Kit (Sandwich ELISA) - LS-F4126 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 0.59 ng/ml Range 4.69-300 ng/ml

Human F2 / Prothrombin / Thrombin ELISA Kit - LS-F10429 from LifeSpan Bioscience Category ELISA Kit Prices $380.00 Sizes 1 plate Sensitivity 0.166 ng/ml Range 0.25 - 100 ng/ml

Mouse F2 / Prothrombin / Thrombin ELISA Kit (Sandwich ELISA) - LS-F10448 from LifeSpan Bioscience Category ELISA Kit Prices $400.00 Sizes 1 plate Sensitivity 0.319 ng/ml Range 4.69-300 ng/ml

Mouse F2 / Prothrombin / Thrombin ELISA Kit (Sandwich ELISA) - LS-F10449 from LifeSpan Bioscience Category ELISA Kit Prices $480.00 Sizes 1 plate Sensitivity 0.386 ng/ml Range 4.69-300 ng/ml

Prothrombin Antibody Pair - 55R-1006 from Fitzgerald Category Antibody Pair Prices $465.00 Sizes 5 plates

Prothrombin screen ELISA kit - 55R-ORG541S from Fitzgerald Category ELISA Kit Prices $275.00 Sizes 96 wells

Human Prothrombin ELISA Kit - abx051860 from Abbexa Category ELISA Kit

Anti-Prothrombin, Human, ELISA Kit - E01A0037 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1 ng/mL Range 0.5-10ng/ml

Prothrombin, Human, ELISA Kit - E01P0044 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/mL,

Serine Protease, PRSS, Human, ELISA Kit - E-EL-H1953 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Prothrombin, PT, Human, ELISA Kit - E-EL-H1792 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 5.625 Range 9.375-600ng/mL

Serine protease, Human, ELISA Kit - E01H1351 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Serine protease, Human, ELISA Kit - E01P0725 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Serine Protease, PRSS, Rabbit, ELISA Kit - E-EL-RB0831 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Prothrombin, PT, Rabbit, ELISA Kit - E-EL-RB2251 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Serine Protease, PRSS, Chicken, ELISA Kit - E-EL-Ch0443 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Prothrombin, PT, Chicken, ELISA Kit - E-EL-Ch0835 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Serine Protease, PRSS, Porcine, ELISA Kit - E-EL-P1666 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Prothrombin, PT, Porcine, ELISA Kit - E-EL-P2187 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

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