RSPO4

Gene Symbol	RSPO4
Entrez Gene	343637
Alt Symbol	C20orf182, CRISTIN4
Species	Human
Gene Type	protein-coding
Description	R-spondin 4
Other Description	R-spondin family, member 4|R-spondin-4|hRspo4|roof plate-specific spondin-4
Swissprots	Q9UGB2 A2A2I6 Q2I0M5
Accessions	EAX10652 EAX10653 Q2I0M5 AK122609 BC156852 AAI56853 BQ185331 DQ355152 ABC75877 XM_011529232 XP_011527534 XM_011529233 XP_011527535 XR_937068 XR_937069 NM_001029871 NP_001025042 NM_001040007 NP_001035096
Function	Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. {ECO:0000269|PubMed:21727895, ECO:0000269|PubMed:21909076}.
Subcellular Location	Secreted {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human R-Spondin 4 DuoSet ELISA - DY4575-05 from R&D Systems Category ELISA Kit Prices $299.00 Sizes 1 kit (for 5 Plates) Range 31.20 - 2,000 pg/mL

R-spondin-4 (RSPO4), Human, ELISA Kit - CSB-EL020553HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

R-spondin family, member 4, ELISA Kit - MBS940621 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human R-spondin-4(RSPO4) ELISA kit - CSB-EL020553HU from Cusabio Category ELISA Kit Sensitivity Request Information Range Request Information

Human R-spondin-4 (RSPO4) ELISA Kit - EKC35424 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

Human R-Spondin-4 PicoKine™ ELISA Kit EK1494 - EK1494 from Boster Bio Category ELISA Kit Prices $369.00 Sizes 1 kit Sensitivity <10pg/ml Range 31.2pg/ml-2000pg/ml *This assay range is determined using common samples. For samples with low target protein concentrations, users can adjust the standard curve to extend the lower limit of assay range.

Human RSPO4 ELISA Kit - CEK1888 from Cohesion Biosciences Category ELISA Kit Prices $380.00 Sizes 96 t Sensitivity 10 pg/ml Range 31.2 pg/ml - 2000 pg/ml

Human RSPO4 ELISA Kit - orb385336 from Biorbyt Category ELISA Kit Prices $536.00 Sizes 96 test Sensitivity 10 pg/ml Range 31.2 pg/ml-2000 pg/ml

Human RSPO4 ELISA Kit - E032623 from Biobool Category ELISA Kit Sensitivity Intra-assay Precision Intra-Assay Precision (Precision within an assay) Three samples of kn

R-Spondin-4, ELISA Kit - MBS178541 from MyBioSource Category ELISA Kit Prices $425.00 Sizes 1x96 wells Sensitivity <10pg/ml Range 31.2pg/ml-2000pg/ml

RSPO4, ELISA Kit - MBS8248395 from MyBioSource Category ELISA Kit Prices $490.00 Sizes 96 tests Sensitivity <10 pg/ml

Human RSPO4 ELISA Kit (Sandwich ELISA) - LS-F39992 from LifeSpan Bioscience Category ELISA Kit Sensitivity 10 pg/ml Range 31.2-2000 pg/ml

Mouse RSPO4 ELISA Kit (Sandwich ELISA) - LS-F31709 from LifeSpan Bioscience Category ELISA Kit Sensitivity 10 pg/ml Range 31.2-2000 pg/ml

Human R-Spondin-4 ELISA Kit - EK5699 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 96 t Range 31.2pg ml-2000pg ml

Human RSPO4 ELISA Kit - orb405254 from Biorbyt Category ELISA Kit

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