Tfam

Gene Symbol Tfam
Entrez Gene 83474
Alt Symbol Mttfa
Species Rat
Gene Type protein-coding
Description transcription factor A, mitochondrial
Other Description -
Swissprots Q91ZW1 Q9WTM7
Accessions AAF74765 EDL97257 EDL97258 EDL97259 Q91ZW1 AB014089 BAA77755 AF246196 AAG09777 AF377866 AAL12892 AJ312746 CAC84763 BC062022 AAH62022 FQ219683 NM_031326 NP_112616
Function Isoform Mitochondrial binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA (By similarity). Isoform Nuclear may also function as a transcriptional activator or may have a structural role in the compaction of nuclear DNA during spermatogenesis (By similarity). {ECO:0000250}.
Subcellular Location Isoform Mitochondrial: Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250}.
Tissue Specificity The mitochondrial isoform is widely expressed while the nuclear isoform is testis-specific.
Top Pathways Huntington's disease

mtTFA Antibody - NBP1-50787 from Novus Biologicals

Prices $245.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: mtTFA Antibody [NBP1-50787] - Rat kidney tissue lysate.

TFAM antibody - 70R-12162 from Fitzgerald

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

TFAM Antibody - abx103959 from Abbexa

Host Rabbit
Clonality Polyclonal

TFAM / TCF6 antibody - PAB9054 from Acris Antibodies

Prices $430.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of Tfam expression in rat kidney tissue lysate.

Rabbit Anti-TFAM Antibody - 168-10677 from RayBiotech

Host Rabbit

Anti-Transcription Factor A, Mitochondrial (TFAM) - 20-5317 from ARP American Research Products

Prices $379.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

TFAM Antibody - 3885-100 from Biovision

Prices $245.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

TFAM, Polyclonal Antibody - MBS840239 from MyBioSource

Prices $150.00, $290.00
Sizes 30 µg, 100 µg
Host Rabbit
Clonality Polyclonal

anti-TFAM antibody - ARG20285 from Arigo Biolaboratories

Host Rabbit
Clonality Polyclonal
ARG20285 anti-TFAM antibody WB image Western Blot: Rat kidney tissue lysate stained with anti-TFAM antibody (ARG20285). The antibody recognizes 27 kDa band from rat kidney tissue lysate.

TFAM-Antibody - ABV10682 from Abgent, a WuXi AppTec company

Prices $89.00, $245.00
Sizes 30 µg, 100 µg
Host Rabbit
Clonality Polyclonal

Transcription Factor A, Mitochondrial (TFAM) Polyclonal Antibody - CAU22071 from Biomatik

Prices $121.00, $282.00, $403.00, $644.00
Sizes 10 μg, 50 μg, 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

mtTFA antibody - GTX59889 from GeneTex

Prices $329.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
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