Tfam

Gene Symbol	Tfam
Entrez Gene	83474
Alt Symbol	Mttfa
Species	Rat
Gene Type	protein-coding
Description	transcription factor A, mitochondrial
Other Description	-
Swissprots	Q91ZW1 Q9WTM7
Accessions	AAF74765 EDL97257 EDL97258 EDL97259 Q91ZW1 AB014089 BAA77755 AF246196 AAG09777 AF377866 AAL12892 AJ312746 CAC84763 BC062022 AAH62022 FQ219683 NM_031326 NP_112616
Function	Isoform Mitochondrial binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA (By similarity). Isoform Nuclear may also function as a transcriptional activator or may have a structural role in the compaction of nuclear DNA during spermatogenesis (By similarity). {ECO:0000250}.
Subcellular Location	Isoform Mitochondrial: Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250}.
Tissue Specificity	The mitochondrial isoform is widely expressed while the nuclear isoform is testis-specific.
Top Pathways	Huntington's disease

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Rat TFAM Protein - abx069401 from Abbexa Category Protein Source E.coli Species Rat

Transcription Factor A, Mitochondrial (TFAM), Rat - 20-9224 from ARP American Research Products Category Protein Prices $619.00 Sizes 50 µg Source E.coli Species Rat

Recombinant Transcription Factor A, Mitochondrial (TFAM) - RPH050Ra01 from Cloud-clone Category Protein Source E.coli Species Rat

Recombinant Rat Transcription factor A, mitochondrial(Tfam) - CSB-YP023413RA CSB-EP023413RA CSB-BP023413RA CSB-MP023413RA from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Rat

Transcription Factor A, Mitochondrial (TFAM) - RPU144106 from Biomatik Category Protein Prices $302.50, $605.00, $907.50 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Rat

TFAM, Peptide - MBS843905 from MyBioSource Category Peptide Prices $165.00 Sizes 50 µg

Recombinant Rat TFAM Protein - TFAM-6024R from Creative Biomart Category Protein Source Mammalian Cells Species Rat

Recombinant Transcription Factor A, Mitochondrial (TFAM) - RPU44106 from Biomatik Category Protein Prices $220.00, $473.00, $722.00, $902.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Rat

TFAM Recombinant Protein (OPCD07334) - OPCD07334 from Aviva Systems Biology Category Protein Source E.coli Species Rat

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