Tfam

Gene Symbol Tfam
Entrez Gene 83474
Alt Symbol Mttfa
Species Rat
Gene Type protein-coding
Description transcription factor A, mitochondrial
Other Description -
Swissprots Q91ZW1 Q9WTM7
Accessions AAF74765 EDL97257 EDL97258 EDL97259 Q91ZW1 AB014089 BAA77755 AF246196 AAG09777 AF377866 AAL12892 AJ312746 CAC84763 BC062022 AAH62022 FQ219683 NM_031326 NP_112616
Function Isoform Mitochondrial binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA (By similarity). Isoform Nuclear may also function as a transcriptional activator or may have a structural role in the compaction of nuclear DNA during spermatogenesis (By similarity). {ECO:0000250}.
Subcellular Location Isoform Mitochondrial: Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250}.
Tissue Specificity The mitochondrial isoform is widely expressed while the nuclear isoform is testis-specific.
Top Pathways Huntington's disease

Transcription factor A, mitochondrial (TFAM), Rat, ELISA Kit - CSB-EL023413RA from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t
Sensitivity 5.8 pg/ml
Range 23.5 pg/ml-1500 pg/ml

transcription factor A, mitochondrial, ELISA Kit - MBS942857 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of rat TFAM is typically less than 5.8 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 23.5 pg/ml -1500 pg/ml.

Transcription Factor A, Mitochondrial, ELISA Kit - MBS066025 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1ng/ml.
Range 0.5ng/ml-16ng/ml.

Rat Transcription factor A, mitochondrial(TFAM) ELISA kit - CSB-EL023413RA from Cusabio

Category ELISA Kit
Sensitivity 5.8 pg/ml
Range 23.5 pg/ml-1500 pg/ml

Rat Transcription factor A, mitochondrial (TFAM) ELISA Kit - EKC39795 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 5.8 pg/ml
Range 23.5 pg/ml-1500 pg/ml

Rat Tfam ELISA Kit - E100120 from Biobool

Category ELISA Kit

TFAM ELISA Kit (Rat) (OKCA01941) - OKCA01941 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 5.8 pg/mL
Range 23.5 - 1,500 pg/mL
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