TMPRSS6

Gene Symbol	TMPRSS6
Entrez Gene	164656
Alt Symbol	IRIDA
Species	Human
Gene Type	protein-coding
Description	transmembrane protease, serine 6
Other Description	matriptase-2|membrane-bound mosaic serine proteinase matriptase-2|transmembrane protease serine 6|type II transmembrane serine protease 6
Swissprots	Q8IUE2 Q6UXD8 Q6ICC2 B0QYB4 B0QYB7 B0QYB8 Q8IU80 Q8IXV8 Q5TI06
Accessions	AAL16413 EAW60141 EAW60142 EAW60143 Q8IU80 AJ319876 CAC85953 AW295507 AY055384 AAL16414 AY358398 AAQ88764 BC039082 AAH39082 CR456446 CAG30332 CU013044 CAK54475 CU013332 CAK54774 XM_006724162 XP_006724225 XM_006724163 XP_006724226 XM_011529987 XP_011528289 XM_011529988 XP_011528290 XM_011529989 XP_011528291 NM_001289000 NP_001275929 NM_001289001 NP_001275930 NM_153609 NP_705837
Function	Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Plays a role in the regulation of iron homeostasis, a process involving HAMP. Required to sense iron deficiency and suppress activation of the HAMP promoter. {ECO:0000269|PubMed:12149247, ECO:0000269|PubMed:18408718}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12149247, ECO:0000269|PubMed:20518742}; Single-pass type II membrane protein {ECO:0000269|PubMed:12149247, ECO:0000269|PubMed:20518742}.
Tissue Specificity	Liver specific. {ECO:0000269|PubMed:12149247}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-TMPRSS6-cDNA-Clone - DC07244 from Abgent, a WuXi AppTec company Prices $622.35 Sizes 10 µg Species Human Accession BC039082

TMPRSS6 - MBS1278190 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC039082

Human TMPRSS6 Gene ORF cDNA clone in cloning vector - HG12317-G from Sino Biological Species Human

Human TMPRSS6 Gene ORF cDNA clone expression plasmid, C-HA tag - HG12317-CY from Sino Biological Species Human

Human TMPRSS6 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12317-NM from Sino Biological Species Human

Human TMPRSS6 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12317-CF from Sino Biological Species Human

Human TMPRSS6 Gene ORF cDNA clone expression plasmid, N-HA tag - HG12317-NY from Sino Biological Species Human

Human TMPRSS6 Gene ORF cDNA clone expression plasmid, N-His tag - HG12317-NH from Sino Biological Species Human

Human TMPRSS6 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12317-CM from Sino Biological Species Human

Human TMPRSS6 Gene ORF cDNA clone expression plasmid - HG12317-UT from Sino Biological Species Human

Human TMPRSS6 Gene ORF cDNA clone expression plasmid, C-His tag - HG12317-CH from Sino Biological Species Human

Human TMPRSS6 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12317-ACG from Sino Biological Species Human

Human TMPRSS6 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12317-NF from Sino Biological Species Human

human TMPRSS6 ORF clone (NM_153609.2) - CDCH093250 from Creative biogene Species Human

Human TMPRSS6 ORF Clone (BC039082) - CDCS417332 from Creative biogene Species Human Accession Q8IU80

Human TMPRSS6 ORF clone (BC039082) - CDCB160123 from Creative biogene Species Human

Human TMPRSS6 cDNA Clone(NM_153609.2) - CDFG010137 from Creative biogene Species Human

Human TMPRSS6 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12317-ACR from Sino Biological Species Human

Human TMPRSS6 Gene cDNA Clone - orb145596 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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