TMPRSS6

Gene Symbol TMPRSS6
Entrez Gene 164656
Alt Symbol IRIDA
Species Human
Gene Type protein-coding
Description transmembrane protease, serine 6
Other Description matriptase-2|membrane-bound mosaic serine proteinase matriptase-2|transmembrane protease serine 6|type II transmembrane serine protease 6
Swissprots Q8IUE2 Q6UXD8 Q6ICC2 B0QYB4 B0QYB7 B0QYB8 Q8IU80 Q8IXV8 Q5TI06
Accessions AAL16413 EAW60141 EAW60142 EAW60143 Q8IU80 AJ319876 CAC85953 AW295507 AY055384 AAL16414 AY358398 AAQ88764 BC039082 AAH39082 CR456446 CAG30332 CU013044 CAK54475 CU013332 CAK54774 XM_006724162 XP_006724225 XM_006724163 XP_006724226 XM_011529987 XP_011528289 XM_011529988 XP_011528290 XM_011529989 XP_011528291 NM_001289000 NP_001275929 NM_001289001 NP_001275930 NM_153609 NP_705837
Function Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Plays a role in the regulation of iron homeostasis, a process involving HAMP. Required to sense iron deficiency and suppress activation of the HAMP promoter. {ECO:0000269|PubMed:12149247, ECO:0000269|PubMed:18408718}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12149247, ECO:0000269|PubMed:20518742}; Single-pass type II membrane protein {ECO:0000269|PubMed:12149247, ECO:0000269|PubMed:20518742}.
Tissue Specificity Liver specific. {ECO:0000269|PubMed:12149247}.

Matriptase-2 CRISPR/Cas9 KO Plasmid (h) - sc-410357 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase-2 HDR Plasmid (h) - sc-410357-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase-2 Double Nickase Plasmid (h) - sc-410357-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase-2 Double Nickase Plasmid (h2) - sc-410357-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase-2 CRISPR Activation Plasmid (h) - sc-410357-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase-2 CRISPR Activation Plasmid (h2) - sc-410357-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase-2 Lentiviral Activation Particles (h) - sc-410357-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase-2 Lentiviral Activation Particles (h2) - sc-410357-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Matriptase-2 siRNA (h) - sc-106207 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Matriptase-2 shRNA Plasmid (h) - sc-106207-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Matriptase-2 shRNA (h) Lentiviral Particles - sc-106207-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN2548 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2548 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05140 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05140

TMPRSS6 siRNA (Human) - CRJ6016 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TMPRSS6 - MBS8226193 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TMPRSS6 (NM_153609.2) - SHH431512 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TMPRSS6(NM_153609.2) - SHL082972 from Creative biogene

Category siRNA
Species Reactivities Human

Human TMPRSS6 siRNA - orb276517 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TMPRSS6 shRNA Plasmid (Human) - CHJ6016 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TMPRSS6 miRNA 3'UTR clone - MiUTR1H-10579 from Creative biogene

Species Reactivities Human
Search more