TMPRSS6

Gene Symbol	TMPRSS6
Entrez Gene	164656
Alt Symbol	IRIDA
Species	Human
Gene Type	protein-coding
Description	transmembrane protease, serine 6
Other Description	matriptase-2|membrane-bound mosaic serine proteinase matriptase-2|transmembrane protease serine 6|type II transmembrane serine protease 6
Swissprots	Q8IUE2 Q6UXD8 Q6ICC2 B0QYB4 B0QYB7 B0QYB8 Q8IU80 Q8IXV8 Q5TI06
Accessions	AAL16413 EAW60141 EAW60142 EAW60143 Q8IU80 AJ319876 CAC85953 AW295507 AY055384 AAL16414 AY358398 AAQ88764 BC039082 AAH39082 CR456446 CAG30332 CU013044 CAK54475 CU013332 CAK54774 XM_006724162 XP_006724225 XM_006724163 XP_006724226 XM_011529987 XP_011528289 XM_011529988 XP_011528290 XM_011529989 XP_011528291 NM_001289000 NP_001275929 NM_001289001 NP_001275930 NM_153609 NP_705837
Function	Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Plays a role in the regulation of iron homeostasis, a process involving HAMP. Required to sense iron deficiency and suppress activation of the HAMP promoter. {ECO:0000269|PubMed:12149247, ECO:0000269|PubMed:18408718}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12149247, ECO:0000269|PubMed:20518742}; Single-pass type II membrane protein {ECO:0000269|PubMed:12149247, ECO:0000269|PubMed:20518742}.
Tissue Specificity	Liver specific. {ECO:0000269|PubMed:12149247}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Matriptase 2 full length protein - ab132358 from Abcam Category Protein Source Wheat germ Species Human

Matriptase 2 peptide - ab41266 from Abcam Category Peptide

Matriptase 2 peptide - ab41267 from Abcam Category Peptide

Matriptase 2 peptide - ab44743 from Abcam Category Peptide

TMPRSS6 Antibody Blocking Peptide - LS-E19191 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TMPRSS6 Antibody Blocking Peptide - LS-E6592 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Matriptase 2 Protein - H00164656-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

TMPRSS6-AntibodyN-term-Blocking-peptide - BP19372a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TMPRSS6 Blocking Peptide - 33R-5200 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TMPRSS6 - H00164656-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

TMPRSS6 fusion protein - ag4076 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Transmembrane Protease, Serine 6 (TMPRSS6) - RPF817Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Transmembrane Protease, Serine 6 (TMPRSS6) - RPF817Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Transmembrane protease serine 6(TMPRSS6) - CSB-YP808531HU CSB-EP808531HU CSB-BP808531HU CSB-MP808531HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TMPRSS6 (C-term DDK tag) - TP710211 from Acris Antibodies Category Protein Prices $399.00 Sizes 20 µg Source SF9 cells Species Human

Recombinant Human TMPRSS6 protein, DDK-tagged - TMPRSS6-127H from Creative Biomart Category Protein Source Insect cells Species Human

Recombinant Human TMPRSS6 protein, GST-tagged - TMPRSS6-126H from Creative Biomart Category Protein Source Wheat Germ Species Human

TMPRSS6 Peptide, Human - M34GP16321H from Creative Peptides Category Peptide Source Synthetic. Species Human

Search more