Gene Symbol | EDA2R |
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Entrez Gene | 60401 |
Alt Symbol | EDA-A2R, EDAA2R, TNFRSF27, XEDAR |
Species | Human |
Gene Type | protein-coding |
Description | ectodysplasin A2 receptor |
Other Description | EDA-A2 receptor|X-linked ectodysplasin-A2 receptor|tumor necrosis factor receptor superfamily member 27|tumor necrosis factor receptor superfamily member XEDAR |
Swissprots | Q8IZA6 Q5VYY0 Q9HAV5 Q5VYX9 Q6UWM2 |
Accessions | EAX05382 Q9HAV5 AF298812 AAG28761 AK296264 BAG58977 AK299018 BAG61098 AK314881 BAG37396 AY152724 AAN73210 AY358735 AAQ89952 AY358736 AAQ89953 BC034919 AAH34919 BP249106 DA215848 DC368837 HQ447632 ADQ32117 XM_005262285 XP_005262342 XM_006724675 XP_006724738 XM_011531000 XP_011529302 XM_011531001 XP_011529303 XM_011531002 XP_011529304 XM_011531003 XP_011529305 XM_011531004 XP_011529306 XM_011531005 XP_011529307 XM_011531006 XP_011529308 XM_011531007 XP_011529309 XR_244499 XR_938404 XR_938405 XR_938406 NM_001199687 NP_001186616 NM_001242310 NP_001229239 NM_021783 NP_068555 NM_001199688 NM_001199689 |
Function | Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6. {ECO:0000269|PubMed:12270937}. |
Subcellular Location | Membrane; Single-pass type III membrane protein. |
Top Pathways | Cytokine-cytokine receptor interaction |
XEDAR (T-14) - sc-15291 from Santa Cruz Biotechnology
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XEDAR (G-5) - sc-377423 from Santa Cruz Biotechnology
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XEDAR (H-78) - sc-366134 from Santa Cruz Biotechnology
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Anti-EDA2R antibody - ab203667 from Abcam
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Anti-EDA2R antibody - ab167224 from Abcam
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Anti-EDA2R antibody - ab37171 from Abcam
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Anti-EDA2R antibody - C-terminal - ab197931 from Abcam
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Anti-EDA2R antibody - C-terminal - ab176498 from Abcam
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Anti-EDA2R antibody - N-terminal - ab134786 from Abcam
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Anti-EDA2R / XEDAR Antibody IHC-plus⢠- LS-B562 from LifeSpan Bioscience
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Anti-EDA2R / XEDAR Antibody - LS-C18555 from LifeSpan Bioscience
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Anti-EDA2R / XEDAR Antibody (aa267-297, AP) - LS-C234853 from LifeSpan Bioscience
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Anti-EDA2R / XEDAR Antibody (aa267-297, APC) - LS-C234854 from LifeSpan Bioscience
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Anti-EDA2R / XEDAR Antibody (aa267-297, FITC) - LS-C234856 from LifeSpan Bioscience
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Anti-EDA2R / XEDAR Antibody (aa267-297, Biotin) - LS-C234855 from LifeSpan Bioscience
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Anti-EDA2R / XEDAR Antibody (aa267-297, PE) - LS-C234861 from LifeSpan Bioscience
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Anti-EDA2R / XEDAR Antibody (aa267-297, Azide-free, HRP) - LS-C249889 from LifeSpan Bioscience
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Anti-EDA2R / XEDAR Antibody (aa266-297) - LS-C321013 from LifeSpan Bioscience
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Anti-EDA2R / XEDAR Antibody IHC-plus⢠- LS-B7278 from LifeSpan Bioscience
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Anti-EDA2R / XEDAR Antibody (aa1-111, Azide-free) - LS-C329120 from LifeSpan Bioscience
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Anti-EDA2R / XEDAR Antibody (aa267-297) - LS-C159507 from LifeSpan Bioscience
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EDA2R/TNFRSF27/XEDAR Antibody - AF1093 from Novus Biologicals
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EDA2R/TNFRSF27/XEDAR Antibody - NBP1-76710 from Novus Biologicals
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EDA2R/TNFRSF27/XEDAR Antibody (3C1) - H00060401-M02 from Novus Biologicals
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EDA2R/TNFRSF27/XEDAR Antibody - H00060401-D01P from Novus Biologicals
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