EDA2R

Gene Symbol	EDA2R
Entrez Gene	60401
Alt Symbol	EDA-A2R, EDAA2R, TNFRSF27, XEDAR
Species	Human
Gene Type	protein-coding
Description	ectodysplasin A2 receptor
Other Description	EDA-A2 receptor|X-linked ectodysplasin-A2 receptor|tumor necrosis factor receptor superfamily member 27|tumor necrosis factor receptor superfamily member XEDAR
Swissprots	Q8IZA6 Q5VYY0 Q9HAV5 Q5VYX9 Q6UWM2
Accessions	EAX05382 Q9HAV5 AF298812 AAG28761 AK296264 BAG58977 AK299018 BAG61098 AK314881 BAG37396 AY152724 AAN73210 AY358735 AAQ89952 AY358736 AAQ89953 BC034919 AAH34919 BP249106 DA215848 DC368837 HQ447632 ADQ32117 XM_005262285 XP_005262342 XM_006724675 XP_006724738 XM_011531000 XP_011529302 XM_011531001 XP_011529303 XM_011531002 XP_011529304 XM_011531003 XP_011529305 XM_011531004 XP_011529306 XM_011531005 XP_011529307 XM_011531006 XP_011529308 XM_011531007 XP_011529309 XR_244499 XR_938404 XR_938405 XR_938406 NM_001199687 NP_001186616 NM_001242310 NP_001229239 NM_021783 NP_068555 NM_001199688 NM_001199689
Function	Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6. {ECO:0000269|PubMed:12270937}.
Subcellular Location	Membrane; Single-pass type III membrane protein.
Top Pathways	Cytokine-cytokine receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human EDA2R protein fragment - ab191641 from Abcam Category Protein Prices $515.00 Sizes 100 µg Source HEK 293 cells Species Human

Human EDA2R full length protein - ab163715 from Abcam Category Protein Source Wheat germ Species Human

Human EDA2R protein fragment - ab163716 from Abcam Category Protein Source Wheat germ Species Human

Human EDA2R protein fragment - ab174561 from Abcam Category Protein Source E. coli Species Human

EDA2R / XEDAR Antibody Blocking Peptide - LS-E5850 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EDA2R/TNFRSF27/XEDAR Partial Recombinant Protein - H00060401-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

EDA2R/TNFRSF27/XEDAR Recombinant Protein - H00060401-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human EDA2R/TNFRSF27/XEDAR Protein - NBP2-23018 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

EDA2R-Antibody-C-term-Blocking-Peptide - BP18402b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human EDA2R/TNFRSF27/XEDAR Fc Chimera, CF - 1093-XD-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Cynomolgus EDA2R protein - orb138728 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells

Human EDA2R (Fc Tag) protein - orb179749 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells Species Human

EDA2R protein (His tag) - 80R-3530 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

EDA2R / TNFRSF27 (1-138, His-tag) - AR51218PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

EDA2R / TNFRSF27 (1-138, His-tag) - AR51218PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

EDA2R / TNFRSF27 - H00060401-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

EDA2R / TNFRSF27 - H00060401-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

EDA2R / TNFRSF27 - H00060401-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

EDA2R / TNFRSF27 - H00060401-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

EDA2R, 1-138aa, Human, His tag, E.coli - 01-P2397 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

TNFRSF27 Recombinant Protein - 96-254 from ProSci Category Protein Prices $375.00 Sizes 100 µg Source HEK293 cells Species Human

EDA2R fusion protein - ag11568 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

EDA2R fusion protein - ag11566 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Ectodysplasin A2 Receptor, Fc-tagged - EDA2R-2098H from Creative Biomart Category Protein Source HEK 293.

Recombinant Human Ectodysplasin A2 Receptor - EDA2R-1606H from Creative Biomart Category Protein Source NSO Cells .

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