EDA2R

Gene Symbol	EDA2R
Entrez Gene	60401
Alt Symbol	EDA-A2R, EDAA2R, TNFRSF27, XEDAR
Species	Human
Gene Type	protein-coding
Description	ectodysplasin A2 receptor
Other Description	EDA-A2 receptor|X-linked ectodysplasin-A2 receptor|tumor necrosis factor receptor superfamily member 27|tumor necrosis factor receptor superfamily member XEDAR
Swissprots	Q8IZA6 Q5VYY0 Q9HAV5 Q5VYX9 Q6UWM2
Accessions	EAX05382 Q9HAV5 AF298812 AAG28761 AK296264 BAG58977 AK299018 BAG61098 AK314881 BAG37396 AY152724 AAN73210 AY358735 AAQ89952 AY358736 AAQ89953 BC034919 AAH34919 BP249106 DA215848 DC368837 HQ447632 ADQ32117 XM_005262285 XP_005262342 XM_006724675 XP_006724738 XM_011531000 XP_011529302 XM_011531001 XP_011529303 XM_011531002 XP_011529304 XM_011531003 XP_011529305 XM_011531004 XP_011529306 XM_011531005 XP_011529307 XM_011531006 XP_011529308 XM_011531007 XP_011529309 XR_244499 XR_938404 XR_938405 XR_938406 NM_001199687 NP_001186616 NM_001242310 NP_001229239 NM_021783 NP_068555 NM_001199688 NM_001199689
Function	Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6. {ECO:0000269|PubMed:12270937}.
Subcellular Location	Membrane; Single-pass type III membrane protein.
Top Pathways	Cytokine-cytokine receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EDA2R 293T Cell Transient Overexpression Lysate(Denatured) - H00060401-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

EDA2R overexpression lysate - LY411924 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

EDA2R/TNFRSF27/XEDAR Overexpression Lysate (Denatured) - H00060401-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

XEDAR (h): 293T Lysate - sc-370816 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Cynomolgus XEDAR / EDA2R HEK293 Cell Lysate (WB positive control) - 90110-C08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Human XEDAR / EDA2R HEK293 Cell Lysate (WB positive control) - 11845-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Cynomolgus XEDAR / EDA2R HEK293 Cell Lysate (WB positive control) - 90110-C02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Human XEDAR / EDA2R HEK293 Cell Lysate (WB positive control) - 11845-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

EDA2R/TNFRSF27/XEDAR Overexpression Lysate (Denatured) - H00060401-T02 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Human XEDAR Human Cells Transfected Lysate (positive control) (denatured) - orb232901 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Human EDA2R Human Cells Transfected Lysate (positive control) (denatured) - orb173724 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human EDA2R Knockdown Stable Cell Line - CSC-DC004705 from Creative biogene Category Cell Line Species Human

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