Gene Symbol | PCDH12 |
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Entrez Gene | 51294 |
Alt Symbol | VE-cadherin-2, VECAD2 |
Species | Human |
Gene Type | protein-coding |
Description | protocadherin 12 |
Other Description | VE-cad-2|VE-cadherin 2|protocadherin-12|vascular cadherin-2|vascular endothelial cadherin 2|vascular endothelial cadherin-2 |
Swissprots | Q9H8E0 Q9H7Y6 Q96KB8 Q6UXB6 Q9NPG4 |
Accessions | EAW61898 Q9NPG4 AB026893 BAA95162 AF231025 AAF61931 AF240635 AAF73962 AK023785 BAB14677 AK024140 BAB14837 AK027282 BAB55016 AK226049 AK315029 BAG37515 AY358428 AAQ88794 BC042634 AAH42634 BC052973 AAH52973 CA418447 NM_016580 NP_057664 |
Function | Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions. Promotes homotypic calcium-dependent aggregation and adhesion and clusters at intercellular junctions. Unable to bind to catenins, weakly associates with the cytoskeleton (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Cell junction. |
Tissue Specificity | Expressed in highly vascularized tissues including the heart and placenta, but most tissues contain a low level of expression. Prominent expression in the spleen. |
VE-cadherin-2 (S-17) - sc-79820 from Santa Cruz Biotechnology
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VE-cadherin-2 (N-14) - sc-79818 from Santa Cruz Biotechnology
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VE-cadherin-2 (H-177) - sc-292329 from Santa Cruz Biotechnology
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VE-cadherin-2 (M-142) - sc-292330 from Santa Cruz Biotechnology
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Anti-PCDH12 antibody - ab113720 from Abcam
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Anti-PCDH12 antibody - ab82885 from Abcam
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Anti-PCDH12 / VE-Cadherin-2 Antibody (aa612-661) - LS-C81021 from LifeSpan Bioscience
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Anti-PCDH12 / VE-Cadherin-2 Antibody (N-Terminus) - LS-C108481 from LifeSpan Bioscience
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Anti-PCDH12 / VE-Cadherin-2 Antibody (N-Terminus) IHC-plus⢠- LS-B4995 from LifeSpan Bioscience
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Protocadherin-12 Antibody - NBP1-59205 from Novus Biologicals
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Protocadherin-12 Antibody - NBP1-77002 from Novus Biologicals
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Protocadherin-12 Antibody - NBP2-13737 from Novus Biologicals
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Rabbit Anti-PCDH12 Polyclonal Antibody - bs-11109R from Bioss
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Rabbit Anti-PCDH12 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11109R-A350 from Bioss
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Rabbit Anti-PCDH12 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11109R-A488 from Bioss
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Rabbit Anti-PCDH12 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11109R-A555 from Bioss
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Rabbit Anti-PCDH12 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11109R-A647 from Bioss
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Rabbit Anti-PCDH12 Polyclonal Antibody, Cy3 Conjugated - bs-11109R-Cy3 from Bioss
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Rabbit Anti-PCDH12 Polyclonal Antibody, Cy5 Conjugated - bs-11109R-Cy5 from Bioss
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Rabbit Anti-PCDH12 Polyclonal Antibody, Cy5.5 Conjugated - bs-11109R-Cy5.5 from Bioss
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Rabbit Anti-PCDH12 Polyclonal Antibody, Cy7 Conjugated - bs-11109R-Cy7 from Bioss
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Rabbit Anti-PCDH12 Polyclonal Antibody, FITC Conjugated - bs-11109R-FITC from Bioss
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Rabbit Anti-PCDH12 Polyclonal Antibody, PE Conjugated - bs-11109R-PE from Bioss
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Rabbit Anti-PCDH12 Polyclonal Antibody, Biotin Conjugated - bs-11109R-Biotin from Bioss
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Rabbit Anti-PCDH12 Polyclonal Antibody, HRP Conjugated - bs-11109R-HRP from Bioss
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