Gene Symbol | PCDH12 |
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Entrez Gene | 51294 |
Alt Symbol | VE-cadherin-2, VECAD2 |
Species | Human |
Gene Type | protein-coding |
Description | protocadherin 12 |
Other Description | VE-cad-2|VE-cadherin 2|protocadherin-12|vascular cadherin-2|vascular endothelial cadherin 2|vascular endothelial cadherin-2 |
Swissprots | Q9H8E0 Q9H7Y6 Q96KB8 Q6UXB6 Q9NPG4 |
Accessions | EAW61898 Q9NPG4 AB026893 BAA95162 AF231025 AAF61931 AF240635 AAF73962 AK023785 BAB14677 AK024140 BAB14837 AK027282 BAB55016 AK226049 AK315029 BAG37515 AY358428 AAQ88794 BC042634 AAH42634 BC052973 AAH52973 CA418447 NM_016580 NP_057664 |
Function | Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions. Promotes homotypic calcium-dependent aggregation and adhesion and clusters at intercellular junctions. Unable to bind to catenins, weakly associates with the cytoskeleton (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Cell junction. |
Tissue Specificity | Expressed in highly vascularized tissues including the heart and placenta, but most tissues contain a low level of expression. Prominent expression in the spleen. |
Human PCDH12 protein fragment - ab182818 from Abcam
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PCDH12 / VE-Cadherin-2 Antibody Blocking Peptide - LS-E30662 from LifeSpan Bioscience
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PCDH12 / VE-Cadherin-2 Antibody Blocking Peptide - LS-E30667 from LifeSpan Bioscience
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Protocadherin-12 Blocking Peptide - NBP1-77002PEP from Novus Biologicals
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PCDH12 Peptide - GTX85342-PEP from GeneTex
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PCDH12 Protein Lysate (APL11053) - APL11053 from Aviva Systems Biology
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PCDH12 Protein Lysate (APL11054) - APL11054 from Aviva Systems Biology
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PCDH12 Protein Lysate (APL11055) - APL11055 from Aviva Systems Biology
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PCDH12 Blocking Peptide - 33R-8846 from Fitzgerald
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Protocadherin-12 / PCDH12 Control Peptide - AP30648CP-N from Acris Antibodies
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PCDH12 Peptide - 5071P from ProSci
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PCDH12 fusion protein - Ag5360 from Proteintech Group
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PCDH12 fusion protein - ag5823 from Proteintech Group
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Recombinant Human PCDH12, GST-tagged - PCDH12-1552H from Creative Biomart
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Recombinant Human Protocadherin-12(PCDH12) - CSB-YP885683HU CSB-EP885683HU CSB-BP885683HU CSB-MP885683HU from Cusabio
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Recombinant Human Protocadherin-12 Protein, CF - 8477-CA from R&D Systems
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Protocadherin-12 / PCDH12 - TP323041 from Acris Antibodies
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Protocadherin-12 Protein - NBP2-13737PEP from Novus Biologicals
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PCDH12 Protein Lysate - orb333629 from Biorbyt
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PCDH12 Peptide, Human - M34GP11372H from Creative Peptides
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PCDH12 Protein Lysate - orb333628 from Biorbyt
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Protocadherin-12 (PCDH12), Recombinant Protein - MBS1446567 from MyBioSource
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Recombinant Human Protocadherin-12 Protein, CF - 8477-CA from Novus Biologicals
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Recombinant Mouse Protocadherin-12 Protein, CF - 7926-CA from Novus Biologicals
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