TNFRSF1B

Gene Symbol	TNFRSF1B
Entrez Gene	7133
Alt Symbol	CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor receptor superfamily, member 1B
Other Description	TNF-R2|TNF-RII|p75 TNF receptor|p80 TNF-alpha receptor|soluble TNFR1B variant 1|tumor necrosis factor beta receptor|tumor necrosis factor binding protein 2|tumor necrosis factor receptor 2|tumor necrosis factor receptor superfamily member 1B|tumor necrosis factor receptor type II
Swissprots	Q16042 B1AJZ3 P20333 Q9UIH1 Q6YI29
Accessions	AAC50622 AAD14848 AAO89076 AAP88939 BAA89052 BAA89053 BAA89054 BAA89055 CAA56324 CAI84623 CAY56003 CBX53870 CCA94575 EAW71731 EAW71732 EAW71733 EAW71734 EAW71735 P20333 AY148473 AAN72434 BC011844 AAH11844 BC042167 AAH42167 BC052977 AAH52977 BT019927 AAV38730 EU826615 ACF47651 M32315 AAA59929 M35857 AAA63262 M55994 AAA36755 S63368 AAB19824 XM_011542060 XP_011540362 XM_011542061 XP_011540363 XM_011542062 XP_011540364 XM_011542063 XP_011540365 NM_001066 NP_001057
Function	Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. {ECO:0000269|PubMed:12370298}.
Subcellular Location	Tumor necrosis factor-binding protein 2: Secreted.
Top Pathways	Cytokine-cytokine receptor interaction, Adipocytokine signaling pathway, Amyotrophic lateral sclerosis (ALS), TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Soluble TNF Receptor II Human ELISA Kit - ab100643 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 5 pg/ml Range 2.74 pg/ml - 2000 pg/ml

Mouse/Human/Rat TNFRSF1B / TNFR2 ELISA Kit (Cell-Based ELISA) - LS-F3067 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 8-500 pg/ml

Mouse TNFRSF1B / TNFR2 ELISA Kit (Sandwich ELISA) - LS-F662 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 8-500 pg/ml

Human TNFRSF1B / TNFR2 ELISA Kit (Sandwich ELISA) - LS-F1030 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 8-500 pg/ml

Rat TNFRSF1B / TNFR2 ELISA Kit (Sandwich ELISA) - LS-F8073 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.056 ng/ml Range 8-500 pg/ml

Human TNFRSF1B / TNFR2 ELISA Kit (Sandwich ELISA) - LS-F8503 from LifeSpan Bioscience Category ELISA Kit Prices $470.00 Sizes 1 plate Sensitivity 0.063 ng/ml Range 8-500 pg/ml

Mouse TNFRSF1B / TNFR2 ELISA Kit (Sandwich ELISA) - LS-F9992 from LifeSpan Bioscience Category ELISA Kit Prices $630.00 Sizes 1 plate Sensitivity 1.6 pg/ml Range 8-500 pg/ml

Human TNFRSF1B / TNFR2 ELISA Kit (Sandwich ELISA) - LS-F2561 from LifeSpan Bioscience Category ELISA Kit Prices $510.00 Sizes 1 plate Sensitivity 2 pg/ml Range 8-500 pg/ml

Mouse TNFRSF1B / TNFR2 ELISA Kit (Sandwich ELISA) - LS-F2562 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 1 pg/ml Range 8-500 pg/ml

Human sTNF RII/TNFRSF1B Quantikine ELISA Kit - DRT200 from R&D Systems Category ELISA Kit Prices $509.00, $2,440.00, $16,540.00 Sizes 1 kit, 1 pack (6 Plates), 1 pack (50 Plates) Sensitivity 2.3 pg/mL Range 7.8 - 500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine)

Human sTNF RII/TNFRSF1B Quantikine PharmPak (50 Plates) - PDRT200 from R&D Systems Category ELISA Kit Sensitivity 2.3 pg/mL Range 7.8 - 500 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, Citrate Plasma, EDTA Plasma, Urine)

Human sTNF RII/TNFRSF1B Quantikine SixPak (6 Plates) - SRT200 from R&D Systems Category ELISA Kit Sensitivity 2.3 pg/mL Range 7.8 - 500 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, Citrate Plasma, EDTA Plasma, Urine)

Human sTNF RII/TNFRSF1B DuoSet ELISA - DY726 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 7.81 - 500 pg/mL

Mouse/Rat TNF RII/TNFRSF1B Quantikine ELISA Kit - MRT20 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 5 pg/mL Range 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma)

Mouse sTNF RII/TNFRSF1B DuoSet ELISA - DY426 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 7.81 - 500 pg/mL

Human TNFR2 ELISA Kit - 55R-1694 from Fitzgerald Category ELISA Kit Prices $385.00 Sizes 1 kit

sTNF-R2 ELISA Kit (Human) : 96 Wells (OKAG00250) - OKAG00250 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 8 pg/mL Range 8-500 pg/mL

Human CD120b ELISA Kit - abx056058 from Abbexa Category ELISA Kit

Soluble tumor necrosis factor receptor 2, sTNF-R2, Human, ELISA Kit - CSB-E11266h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.156 ng/ml Range 0.625 ng/ml-40 ng/ml

sTNFR2, Human, ELISA Kit - BEK1217 from ARP American Research Products Category ELISA Kit Prices $529.00 Sizes 96 t Sensitivity < 2pg/ml Range 7.8 pg/ml-500 pg/ml

Tumor Necrosis Factor Receptor Superfamily, Member 1B, TNFRSF1B, Human, ELISA Kit - E-EL-H2436 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 4.688 Range 7.813-500pg/mL

Tumor Necrosis Factor Receptor 2, Human, ELISA Kit - E01T0568 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Tumor necrosis factor receptor superfamily member 1B, TNFRSF1B, Human, ELISA Kit - E0132h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 15.6-1000 pg/ml

Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B), Human, ELISA Kit - SEB504Hu from ARP American Research Products Category ELISA Kit Prices $468.00 Sizes 96 t Sensitivity 0.063ng/mL Range 0.156-10ng/mL

Tumor Necrosis Factor Receptor Superfamily, Member 1B, TNFRSF1B, Mouse, ELISA Kit - E-EL-M0643 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 4.688 Range 7.813-500pg/mL

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