TNFRSF1B

Gene Symbol	TNFRSF1B
Entrez Gene	7133
Alt Symbol	CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor receptor superfamily, member 1B
Other Description	TNF-R2|TNF-RII|p75 TNF receptor|p80 TNF-alpha receptor|soluble TNFR1B variant 1|tumor necrosis factor beta receptor|tumor necrosis factor binding protein 2|tumor necrosis factor receptor 2|tumor necrosis factor receptor superfamily member 1B|tumor necrosis factor receptor type II
Swissprots	Q16042 B1AJZ3 P20333 Q9UIH1 Q6YI29
Accessions	AAC50622 AAD14848 AAO89076 AAP88939 BAA89052 BAA89053 BAA89054 BAA89055 CAA56324 CAI84623 CAY56003 CBX53870 CCA94575 EAW71731 EAW71732 EAW71733 EAW71734 EAW71735 P20333 AY148473 AAN72434 BC011844 AAH11844 BC042167 AAH42167 BC052977 AAH52977 BT019927 AAV38730 EU826615 ACF47651 M32315 AAA59929 M35857 AAA63262 M55994 AAA36755 S63368 AAB19824 XM_011542060 XP_011540362 XM_011542061 XP_011540363 XM_011542062 XP_011540364 XM_011542063 XP_011540365 NM_001066 NP_001057
Function	Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. {ECO:0000269|PubMed:12370298}.
Subcellular Location	Tumor necrosis factor-binding protein 2: Secreted.
Top Pathways	Cytokine-cytokine receptor interaction, Adipocytokine signaling pathway, Amyotrophic lateral sclerosis (ALS), TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CD120b / TNFR2 Lysate(Denatured) - H00007133-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

TNFRSF1B overexpression lysate - LY400436 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

TNFRSF1B 293 Cell Lysate - 400452 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Disease Tumor

TNF RII/TNFRSF1B Overexpression Lysate (Denatured) - H00007133-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

TNF RII/TNFRSF1B Overexpression Lysate (Native) - NBL1-17155 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TNF-R2 (h): 293T Lysate - sc-116422 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

TNFRSF1B Over-expression Lysate Product - GWB-42D38C from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Cynomolgus TNFR2 / CD120b / TNFRSF1B HEK293 Cell Lysate (WB positive control) - 90102-C08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Cynomolgus TNFR2 / CD120b / TNFRSF1B HEK293 Cell Lysate (WB positive control) - 90102-C02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Cynomolgus

Human TNFR2 / CD120b / TNFRSF1B HEK293 Cell Lysate (WB positive control) - 10417-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human TNFR2 / CD120b / TNFRSF1B (aa 1-268, 196 Met/Arg) HEK293 Cell Lysate (WB positive control) - 10417-H08H1L-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human TNFR2 / CD120b / TNFRSF1B HEK293 Cell Lysate (WB positive control) - 10417-H03HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human TNFRSF1B Human Cells Transfected Lysate (positive control) (denatured) - orb173201 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Human TNFRSF1B (aa 1-268, 196 Met / Arg) Human Cells Transfected Lysate (positive control) (denatured) - orb175529 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Human TNFRSF1B Human Cells Transfected Lysate (positive control) (denatured) - orb173020 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human TNFRSF1B Knockdown Stable Cell Line - CSC-DC016364 from Creative biogene Category Cell Line Species Human

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