TNFRSF1B

Gene Symbol	TNFRSF1B
Entrez Gene	7133
Alt Symbol	CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor receptor superfamily, member 1B
Other Description	TNF-R2|TNF-RII|p75 TNF receptor|p80 TNF-alpha receptor|soluble TNFR1B variant 1|tumor necrosis factor beta receptor|tumor necrosis factor binding protein 2|tumor necrosis factor receptor 2|tumor necrosis factor receptor superfamily member 1B|tumor necrosis factor receptor type II
Swissprots	Q16042 B1AJZ3 P20333 Q9UIH1 Q6YI29
Accessions	AAC50622 AAD14848 AAO89076 AAP88939 BAA89052 BAA89053 BAA89054 BAA89055 CAA56324 CAI84623 CAY56003 CBX53870 CCA94575 EAW71731 EAW71732 EAW71733 EAW71734 EAW71735 P20333 AY148473 AAN72434 BC011844 AAH11844 BC042167 AAH42167 BC052977 AAH52977 BT019927 AAV38730 EU826615 ACF47651 M32315 AAA59929 M35857 AAA63262 M55994 AAA36755 S63368 AAB19824 XM_011542060 XP_011540362 XM_011542061 XP_011540363 XM_011542062 XP_011540364 XM_011542063 XP_011540365 NM_001066 NP_001057
Function	Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. {ECO:0000269|PubMed:12370298}.
Subcellular Location	Tumor necrosis factor-binding protein 2: Secreted.
Top Pathways	Cytokine-cytokine receptor interaction, Adipocytokine signaling pathway, Amyotrophic lateral sclerosis (ALS), TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat TNF RII/TNFRSF1B (NP_569110) VersaClone cDNA - RDC0364 from R&D Systems Prices $199.00 Sizes 10 µg Species Rat

TNFRSF1B - MBS1278225 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC052977

Human TNFRSF1B cDNA clone(NM_001066.2) - CDFH020008 from Creative Biomart Species Human Accession NM_001066.2

Human TNFRSF1B ORF Clone(NM_001066.2) - CDCR344953 from Creative Biomart Species Human Accession NM_001066.2

Human TNFRSF1B ORF Clone(NM_001066.2) - CDCR344954 from Creative Biomart Species Human Accession NM_001066.2

Human TNFRSF1B ORF Clone(NM_001066.2) - CDCL179226 from Creative Biomart Species Human Accession NM_001066.2

human TNFRSF1B ORF clone - CDCH093528 from Creative Biomart Species Human Accession NM_001066

human TNFRSF1B ORF clone - CDCH093529 from Creative Biomart Species Human Accession NM_001066

Human TNFR2/TNFRSF1B/CD120b Gene ORF cDNA clone in cloning vector - HG10417-M from Sino Biological Species Human

Human TNFR2/TNFRSF1B/CD120b Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10417-ACR from Sino Biological Species Human

Human TNFR2/TNFRSF1B/CD120b Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10417-ACG from Sino Biological Species Human

Human TNFR2/TNFRSF1B/CD120b Gene ORF cDNA clone expression plasmid, N-His tag - HG10417-NH from Sino Biological Species Human

Human TNFRII Gene cDNA Clone (full-length ORF Clone) expression ready, FLAG-tagged - HG10417-M-F from Sino Biological Species Human Accession NM_001066.2

Human TNFR2/TNFRSF1B/CD120b Gene ORF cDNA clone expression plasmid - HG10417-UT from Sino Biological Species Human

Human TNFR2/TNFRSF1B/CD120b Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10417-NF from Sino Biological Species Human

Human TNFR2/TNFRSF1B/CD120b Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10417-NM from Sino Biological Species Human

Human TNFR2/TNFRSF1B/CD120b Gene ORF cDNA clone expression plasmid, C-HA tag - HG10417-CY from Sino Biological Species Human

Human TNFR2/TNFRSF1B/CD120b Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10417-CF from Sino Biological Species Human

Human TNFR2/TNFRSF1B/CD120b Gene ORF cDNA clone expression plasmid, N-HA tag - HG10417-NY from Sino Biological Species Human

Human TNFR2/TNFRSF1B/CD120b Gene ORF cDNA clone expression plasmid, C-His tag - HG10417-CH from Sino Biological Species Human

Human TNFR2/TNFRSF1B/CD120b Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10417-CM from Sino Biological Species Human

Human TNFRII ORF clone(NM_001066.2) - CDCL186524 from Creative biogene Species Human

Human TNFRSF1B ORF Clone (BC052977) - CDCS407177 from Creative biogene Species Human Accession P20333

Human TNFRSF1B cDNA Clone(NM_001066.2) - CDFH020008 from Creative biogene Species Human

Mouse TNF RII/TNFRSF1B (NP_035740) VersaClone cDNA - RDC1919 from R&D Systems Prices $199.00 Sizes 10 µg Species Mouse

Search more