CETN2

Gene Symbol CETN2
Entrez Gene 1069
Alt Symbol CALT, CEN2
Species Human
Gene Type protein-coding
Description centrin, EF-hand protein, 2
Other Description caltractin (20kD calcium-binding protein)|centrin-2
Swissprots Q53XW1 B2R4T4 P41208
Accessions AAW82436 EAW72900 P41208 AK311940 BAG34881 AM393039 CAL37917 BC005334 AAH05334 BC013873 AAH13873 BT007256 AAP35920 X72964 CAA51467 NM_004344 NP_004335
Function The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn rec
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus {ECO:0000305}. Note=Centrosome of S-phase, interphase and mitotic cells.
Top Pathways Nucleotide excision repair

Human CETN2 Gene cDNA Clone - orb142476 from Biorbyt

Prices $255.00
Sizes 10 μg
Species Human

Human-CETN2-cDNA-Clone - DC01731 from Abgent, a WuXi AppTec company

Prices $232.20
Sizes 10 µg
Species Human
Accession BC005334

CETN2 - MBS1270806 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC005334

Human CETN2 cDNA clone(NM_004344.1) - CDFH003505 from Creative Biomart

Species Human
Accession NM_004344.1

Human CETN2 ORF Clone(NM_004344.1) - CDCL158619 from Creative Biomart

Species Human
Accession NM_004344.1

Human CETN2 ORF Clone(NM_004344.1) - CDCR287825 from Creative Biomart

Species Human
Accession NM_004344.1

Human CETN2 ORF Clone(NM_004344.1) - CDCR287826 from Creative Biomart

Species Human
Accession NM_004344.1

Human CETN2 ORF Clone(NM_004344.1) - CDCR287827 from Creative Biomart

Species Human
Accession NM_004344.1

Human CETN2 ORF clone (NM_004344.1) - CDCR046290 from Creative biogene

Species Human

Human CETN2 ORF Clone (BC005334) - CDCS411742 from Creative biogene

Species Human
Accession P41208

Human CETN2 ORF clone (BC005334) - CDCB158546 from Creative biogene

Species Human
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