CETN2

Gene Symbol CETN2
Entrez Gene 1069
Alt Symbol CALT, CEN2
Species Human
Gene Type protein-coding
Description centrin, EF-hand protein, 2
Other Description caltractin (20kD calcium-binding protein)|centrin-2
Swissprots Q53XW1 B2R4T4 P41208
Accessions AAW82436 EAW72900 P41208 AK311940 BAG34881 AM393039 CAL37917 BC005334 AAH05334 BC013873 AAH13873 BT007256 AAP35920 X72964 CAA51467 NM_004344 NP_004335
Function The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn rec
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus {ECO:0000305}. Note=Centrosome of S-phase, interphase and mitotic cells.
Top Pathways Nucleotide excision repair

Centrin-2 CRISPR/Cas9 KO Plasmid (h) - sc-400867 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Centrin-2 HDR Plasmid (h) - sc-400867-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Centrin-2 Double Nickase Plasmid (h) - sc-400867-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Centrin-2 Double Nickase Plasmid (h2) - sc-400867-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Centrin-2 CRISPR Activation Plasmid (h) - sc-400867-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Centrin-2 CRISPR Activation Plasmid (h2) - sc-400867-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Centrin-2 Lentiviral Activation Particles (h) - sc-400867-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Centrin-2 Lentiviral Activation Particles (h2) - sc-400867-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Centrin-2 siRNA (h) - sc-43681 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Centrin-2 shRNA Plasmid (h) - sc-43681-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Centrin-2 shRNA (h) Lentiviral Particles - sc-43681-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Centrin 2 RNAi - H00001069-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU137031 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5991 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5991 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CETN2 siRNA (Human) - CRH0770 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CETN2 - MBS8237354 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Centrin-2 CRISPR/Cas9 KO Plasmid (h2) - sc-400867-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Centrin-2 HDR Plasmid (h2) - sc-400867-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human CETN2 (NM_004344.1) - SHH262329 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CETN2(NM_004344.1) - SHG169179 from Creative biogene

Category siRNA
Species Reactivities Human

Human CETN2 siRNA - orb261272 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CETN2 shRNA Plasmid (Human) - CHH0770 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CETN2 miRNA 3'UTR clone - MiUTR1H-02069 from Creative biogene

Species Reactivities Human
Search more