CETN2

Gene Symbol	CETN2
Entrez Gene	1069
Alt Symbol	CALT, CEN2
Species	Human
Gene Type	protein-coding
Description	centrin, EF-hand protein, 2
Other Description	caltractin (20kD calcium-binding protein)|centrin-2
Swissprots	Q53XW1 B2R4T4 P41208
Accessions	AAW82436 EAW72900 P41208 AK311940 BAG34881 AM393039 CAL37917 BC005334 AAH05334 BC013873 AAH13873 BT007256 AAP35920 X72964 CAA51467 NM_004344 NP_004335
Function	The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn rec
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus {ECO:0000305}. Note=Centrosome of S-phase, interphase and mitotic cells.
Top Pathways	Nucleotide excision repair

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Centrin 2 full length protein - ab116203 from Abcam Category Protein Source E. coli Species Human

Centrin 2 Partial Recombinant Protein - H00001069-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Centrin 2 Recombinant Protein - H00001069-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Centrin 2 Protein - NBP1-50938 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 50 µg, 250 µg Source E. coli Species Human

CETN2 Protein (OPPA00045) - OPPA00045 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source Escherichia Coli.

Human CETN2 protein - orb168102 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E. coli

Human CETN2 (His Tag) protein - orb232344 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Species Human

Human CETN2 protein (His Tag) - orb138533 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli Species Human

CETN2 protein (His tag) - 80R-1613 from Fitzgerald Category Protein Prices $255.00 Sizes 50 µg Source E.coli

Centrin-2 (1-172, His-tag) - AR09794PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

Centrin-2 (1-172, His-tag) - AR09794PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

Centrin-2 - H00001069-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Centrin-2 - H00001069-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Centrin-2 - H00001069-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Centrin-2 - H00001069-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Centrin-2, Human Recombinant - 228-12780-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Centrin-2 - 228-12780-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Centrin-2 - 228-12780-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

CETN2, 1-172aa, His tag, Human, E.coli - 01-1926-2 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

Centrin 2 fusion protein - Ag8567 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Centrin 2 fusion protein - Ag8638 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

CETN2 fusion protein - Ag23253 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PGEX-4T Species Human

Recombinant Human Centrin-2 Protein - BP001877-PRO-060 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

CETN2, 1-172aa, Recombinant Protein - GWB-P1184A from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 50 μg, 250 μg Source E.coli Species Human

CETN2 Human Protein - GWB-BSP426 from Genway Biotech Category Protein Prices $75.00, $165.00, $6,190.00 Sizes 2 μg, 10 μg, 1000 μg Source Escherichia Coli. Species Human

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