CETN2

Gene Symbol	CETN2
Entrez Gene	1069
Alt Symbol	CALT, CEN2
Species	Human
Gene Type	protein-coding
Description	centrin, EF-hand protein, 2
Other Description	caltractin (20kD calcium-binding protein)|centrin-2
Swissprots	Q53XW1 B2R4T4 P41208
Accessions	AAW82436 EAW72900 P41208 AK311940 BAG34881 AM393039 CAL37917 BC005334 AAH05334 BC013873 AAH13873 BT007256 AAP35920 X72964 CAA51467 NM_004344 NP_004335
Function	The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn rec
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus {ECO:0000305}. Note=Centrosome of S-phase, interphase and mitotic cells.
Top Pathways	Nucleotide excision repair

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Centrin-2 Antibody - 2091 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Polyclonal

Centrin-2 (S-19) - sc-27794 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-Centrin 2 antibody - ab196554 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Centrin 2 antibody - ab167496 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-Centrin 2 antibody - ab192413 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Centrin 2 antibody - ab54525 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-Centrin 2 with anti-GAPDH internal loading control antibody - ab80863 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CETN2 / Centrin 2 Antibody (FITC) - LS-C317897 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CETN2 / Centrin 2 Antibody - LS-C306912 from LifeSpan Bioscience Prices $455.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-CETN2 / Centrin 2 Antibody - LS-C317898 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CETN2 / Centrin 2 Antibody - LS-C41157 from LifeSpan Bioscience Prices $225.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-CETN2 / Centrin 2 Antibody (HRP) - LS-C317905 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CETN2 / Centrin 2 Antibody (Biotin) - LS-C318971 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CETN2 / Centrin 2 Antibody - LS-C341785 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CETN2 / Centrin 2 Antibody (clone 3F8) - LS-C196900 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3F8

Anti-CETN2 / Centrin 2 Antibody - LS-C334034 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Centrin 2 Antibody (3F8) - H00001069-M01 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3F8

Centrin 2 Antibody - NBP1-88213 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Centrin 2 Antibody - NB100-78483 from Novus Biologicals Prices $369.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Centrin 2 Antibody - H00001069-B01 from Novus Biologicals Prices $349.00 Sizes 50 µl Host Mouse Clonality Polyclonal

Centrin 2 Antibody - H00001069-A02 from Novus Biologicals Prices $269.00 Sizes 50 µl Host Mouse Clonality Polyclonal

Centrin 2 Antibody - H00001069-B01P from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-CETN2 antibody produced in rabbit - HPA028956 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Monoclonal Anti-CETN2 antibody produced in mouse - WH0001069M1 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3F8

CETN2-Antibody-monoclonal-M01 - AT1504a from Abgent, a WuXi AppTec company Prices $315.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3F8

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